ビオチン

Biotin, vitamin B7 or vitamin H is an essential coenzyme in the metabolism of fat and in other metabolic reactions. It is classified within the group of vitamin B.

At the date of the last update, there was no published data available on its excretion in human milk but, given its lack of toxicity, it is unlikely that there is any risk of its consumption at recommended doses.

Breastfeeding can be continued even with high doses (2.5 mg/day) of biotin. ^{(Sauberan 2019)}

Biotin is found in the non-fat portion of breastmilk in an amount of 5 to 10 μg/L ^{(Sauberan 2019, Sakurai 2005, Mock 1992)} with a higher concentration in mature milk than in colostrum, but without significant differences between preterm milk and full-term milk ^{(Salmenperä 1985, Ford 1983)}, nor between different countries. ^{(Nguyen 2020)}

Biotin requirements are 10 to 200 μg daily according to some authors and 30 to 100 μg according to others: 5 to 15 μg in infants, 20 to 30 μg in children, 30 μg in pregnant women and 35 μg in nursing mothers. ^{(Saleem 2021, Sauberan 2019, Ares 2015, Perry 2014, UMMC 2013, Zempleni 1999)}

Biotin is widely distributed in food. Foods rich in biotin are egg yolk, liver, cereals (wheat, oats), vegetables (spinach, mushrooms), rice, dairy products, and human milk; intestinal bacteria can produce biotin ^{(Saleem 2021),} so its deficiency is very rare under adequate nutritional conditions and there are no known cases of poisoning even with doses higher than those of daily needs.

With a varied and balanced diet, vitamin supplements are not needed for most women.