Last update Aug. 12, 2014

Atropine

Very Low Risk

Safe. Compatible. Minimal risk for breastfeeding and infant.

Either isolated dose or topical medication are safe for breastfed babies.

Anti-cholinergic drugs decrease Prolactin and Oxytocin hormone secretion. Long-standing Atropine treatment could affects mother's milk production.

American Academy of Pediatrics: Maternal Medication Usually Compatible With Breastfeeding.

Alternatives

We do not have alternatives for Atropine since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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Group

Atropine belongs to this group or family:

Tradenames

Main tradenames from several countries containing Atropine in its composition:

List of 18 tradenames
  • Atropinol™
  • Atropisol™
  • Atropt™
  • Barbidonna™
  • Buton™. Contains other elements than Atropine in its composition
  • Causat™. Contains other elements than Atropine in its composition
  • Colestase™. Contains other elements than Atropine in its composition
  • Colicor™. Contains other elements than Atropine in its composition
  • Dipatropin™. Contains other elements than Atropine in its composition
  • Dolospam™. Contains other elements than Atropine in its composition
  • Dymotil™. Contains other elements than Atropine in its composition
  • Eumidral™. Contains other elements than Atropine in its composition
  • Lofenoxal™. Contains other elements than Atropine in its composition
  • Logen™. Contains other elements than Atropine in its composition
  • Migrane™. Contains other elements than Atropine in its composition
  • Neo-Diophen™. Contains other elements than Atropine in its composition
  • Retardin™. Contains other elements than Atropine in its composition
  • Yanal™. Contains other elements than Atropine in its composition

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 90 %
Molecular weight 289 daltons
Protein Binding 14 %
Tmax 1 hours
T½ 4.3 hours

References

  1. Reece-Stremtan Sarah, Campos Matilde, Kokajko Lauren, and The Academy of Breastfeeding Medicine. Breastfeeding Medicine. ABM Clinical Protocol #15: Analgesia and Anesthesia for the Breastfeeding Mother, Revised 2017. Breastfeed Med. 2017 Nov;12(9):500-506. Full text (link to original source) Full text (in our servers)
  2. Chen LH, Zeind C, Mackell S, LaPointe T, Mutsch M, Wilson ME. Breastfeeding travelers: precautions and recommendations. J Travel Med. 2010 Jan-Feb;17(1):32-47. Abstract Full text (link to original source) Full text (in our servers)
  3. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Full text (link to original source) Full text (in our servers)
  4. AAP - American Academy of Pediatrics Committee on Drugs. Transfer of drugs and other chemicals into human milk. Pediatrics. 2001 Sep;108(3):776-89. Abstract Full text (link to original source) Full text (in our servers)
  5. Hagemann TM. Gastrointestinal medications and breastfeeding. J Hum Lact. 1998 Sep;14(3):259-62. Review. Abstract
  6. Lee JJ, Rubin AP. Breast feeding and anaesthesia. Anaesthesia. 1993 Jul;48(7):616-25. Review. Abstract Full text (link to original source) Full text (in our servers)
  7. De Martino F, De Matteo A, L'Abbate V, Soricelli A, Fontana A, Petrenga E, Cesarone M. [Inhibitory effects of atropine on serum prolactin levels after TRH stimulation]. Boll Soc Ital Biol Sper. 1980 Abstract
  8. Bizzarro A, Iannucci F, Tolino A, Soricelli A, Guarino G, Verdoliva A. Inhibiting effect of atropine on prolactin blood levels after stimulation with TRH. Clin Exp Obstet Gynecol. 1980 Abstract

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