Last update March 31, 2023

Anti-Tetanus immunoglobulin

Compatible

Safe product and/or breastfeeding is the best option.

Immunoglobulins (Ig) are proteins produced by B lymphocytes as a humoral response to antigens foreign to the body itself. The immunoglobulins used in clinical practice are preparations from human serum or plasma that contain antibodies, mainly IgG. 

Human tetanus immunoglobulin mainly contains immunoglobulin G (IgG) with a high content of specific antibodies against the toxin of Clostridium tetani. It is obtained from plasma or serum of adult human donors who have been immunised with tetanus vaccine.

Its very high molecular weight make it highly unlikely that significant quantities will pass into breast milk. Administration of standard immunoglobulin does not significantly alter the levels of immunoglobulins (IgG or IgM) in colostrum or breast milk. (Palmeira 2009)

Expert authors consider the use of this medication safe during breastfeeding. (LactMed, Briggs 2015)

List of WHO essential medicines: compatible with breastfeeding. (WHO / UNICEF 2002)


See below the information of these related products:

Alternatives

We do not have alternatives for Anti-Tetanus immunoglobulin since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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José María Paricio, founder of e-lactancia.
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Other names

Anti-Tetanus immunoglobulin is also known as


Anti-Tetanus immunoglobulin in other languages or writings:

Group

Anti-Tetanus immunoglobulin belongs to this group or family:

Tradenames

Main tradenames from several countries containing Anti-Tetanus immunoglobulin in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 0 %
Molecular weight ≈ 150.000 daltons
Tmax 72 hours
T½ 504 - 672 hours

References

  1. Briggs GG, Freeman RK, Towers CV, Forinash AB. Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk. Wolters Kluwer Health. Tenth edition (acces on line) 2015
  2. Palmeira P, Costa-Carvalho BT, Arslanian C, Pontes GN, Nagao AT, Carneiro-Sampaio MM. Transfer of antibodies across the placenta and in breast milk from mothers on intravenous immunoglobulin. Pediatr Allergy Immunol. 2009 Sep;20(6):528-35. Abstract
  3. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Abstract Full text (link to original source) Full text (in our servers)

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