Last update Nov. 1, 2015
Likely Compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Alendronic Acid is also known as Alendronate Sodium.
Alendronic Acid in other languages or writings:
Alendronic Acid belongs to this group or family:
Main tradenames from several countries containing Alendronic Acid in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 0.7 | % |
Molecular weight | 325 | daltons |
Protein Binding | 78 | % |
VD | 0.4 | l/Kg |
T½ | < 3 | hours |
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e-lactancia is a resource recommended by El Parto Es Nuestro of Spain
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It is composed by bisphosphonates.
Most bisphosphonates are acidic compounds that achieve low plasma concentration. Both features make it unlikely excretion into the milk in clinically significant amount.
Alendronate has shown very low plasma concentrations (<5 ng / ml).
Intestinal absorption of bisphosphonates is very low even during fasting and is considered negligible in the presence of milk due to formation with the calcium of non absorbable compounds.
A latest update no published data were found on excretion in the breast milk.
Until more data about this drug regarding breastfeeding is available, safer known alternatives (e.g. pamidronate) should be of choice, especially in the neonatal period and in case of prematurity.