Last update Feb. 15, 2016
Compatible
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Acetylspiramycin is also known as Spiramycin.
Acetylspiramycin in other languages or writings:
Acetylspiramycin belongs to this group or family:
Main tradenames from several countries containing Acetylspiramycin in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 30 - 40 | % |
Molecular weight | 843 | daltons |
Protein Binding | 10 - 25 | % |
VD | 3.8 - 7.4 | l/Kg |
Tmax | 0.5 - 4 | hours |
T½ | 2 - 8 | hours |
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
It is assumed that excretion into breast milk achieves bacteriostatic concentrations.
A latest update no published data were found on excretion into breast milk.
Because a high molecular weight it seems unlikely an excretion into breast milk in significant amount.
A low oral bioavailability further reduced with simultaneous food intake impairs the appearance in the infant plasma from ingested milk except in preterm babies and those in the immediate neonatal period, which may have increased intestinal permeability.
Macrolide-based medication that is used in infants.
Until more published data on this drug regarding breastfeeding is available, safer alternatives with better known drugs should be preferable especially during the neonatal period and in case of prematurity..
Take into account the possible negative cultures in febrile infants whose mothers take antibiotics