Last update Aug. 20, 2023
Compatible
We do not have alternatives for 3-Amino-N-(α-methoxycarbonylphenethyl)succinamic acid; N-l-α-aspartyl-l-phenylalanine, 1-methyl ester; Methyl N-l-α-aspartyl-l-phenylalaninate since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.
3-Amino-N-(α-methoxycarbonylphenethyl)succinamic acid; N-l-α-aspartyl-l-phenylalanine, 1-methyl ester; Methyl N-l-α-aspartyl-l-phenylalaninate is Aspartame in Chemical name.
Is written in other languages:3-Amino-N-(α-methoxycarbonylphenethyl)succinamic acid; N-l-α-aspartyl-l-phenylalanine, 1-methyl ester; Methyl N-l-α-aspartyl-l-phenylalaninate is also known as
3-Amino-N-(α-methoxycarbonylphenethyl)succinamic acid; N-l-α-aspartyl-l-phenylalanine, 1-methyl ester; Methyl N-l-α-aspartyl-l-phenylalaninate belongs to this group or family:
Main tradenames from several countries containing 3-Amino-N-(α-methoxycarbonylphenethyl)succinamic acid; N-l-α-aspartyl-l-phenylalanine, 1-methyl ester; Methyl N-l-α-aspartyl-l-phenylalaninate in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 100 | % |
Molecular weight | 294 | daltons |
T½ | 70 - 100 | hours |
Write us at elactancia.org@gmail.com
e-lactancia is a resource recommended by IHAN of Spain
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Aspartame is a sweetener 180 to 200 times sweeter than sugar (sucrose). Each gram provides 4 kcal.
After digestion, aspartame is rapidly broken down into aspartic acid, phenylalanine and methanol, which are absorbed into the blood and used in normal body processes. The first two components are also found naturally in meats, cereals and dairy products, and the third in fruits and vegetables. They do not accumulate in the body.
It is used as a dietary supplement and sugar substitute, in foods, beverages and pharmaceuticals.
The maximum daily intake of aspartame accepted by the FDA is 50 mg/kg. (Franz 1986)
Aspartame is not detected in breast milk (Sylvetsky 2015, Stegink 1979). After administration of very high amounts of aspartame, the phenylalanine concentration in breast milk was elevated less than 2% of usual during the first 8 hours (Stegink 1979), being still much lower than the phenylalanine concentration in artificial infant substitutes.
Expert authors consider aspartame consumption compatible with breastfeeding. (Cavagnari 2019, Nice 2000)