Last update Aug. 17, 2019
Very Low Risk
A polyphenol (3,5,4’-trihydroxystilbene) derived from grapes and other vegetables such as arachis (peanut), pinus, veratrum and fallopia japonica (polygonum cuspidatum; reynoutria japonica, hu zhang).
It is found in musts and wines in variable but small quantities.
It is a bioflavonoid to which are attributed these properties: antioxidant, venoprotective, cardioprotective, properties against arteriosclerosis, acne and cancer, among others. None of these properties has been sufficiently proven (MedlinePlus 2018).
Since the last update we have not found published data on its excretion in breastmilk.
Oral bioavailability is very low: although it is well absorbed in the intestine, a first-pass metabolism makes the concentration of resveratrol in plasma insignificant (Almeida 2009, Wenzel 2005, Walle 2004).
This low oral bioavailability means that significant amounts cannot transfer to breastmilk. For the same reason, transfer from breastmilk to infant plasma is impeded, except in premature infants and the immediate neonatal period when there may be greater intestinal permeability.
Resveratrol from food and supplements taken orally at non-high doses would be compatible with breastfeeding.
It inhibits prolactin secretion in vitro (Wang 2012).
We do not have alternatives for 3,4′,5-Trihydroxystilbene since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.
e-lactancia is a resource recommended by Asociación Pro Lactancia Materna (APROLAM) of Mexico
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM