Last update: Jan. 7, 2018

ジオスミン

Very Low Risk for breastfeeding


Safe. Compatible.
Not risky for breastfeeding or infant.

Bioflavonoid like substance.

Flavonoids are phenolic compounds naturally occurring that are abundantly present in plants and seaweed.

We take it from fruits, vegetables, tea and red wine (as a few examples)

Most important types are: anthocyanins, chalcons, flavonols, flavones, flavonoids and tannins. No risk for toxic nor side-effects in humans have been found.

They appear naturally in the breast milk in amounts related to mother's diet.

Attributed anti-oxidant activity and other properties that have not been fully shown yet (Martinez 2016, Cohen 2012), as amelioration of capillary vessel function which is a reason to be used for treatment of venous insufficiency (varicose veins) and prevention of arteriosclerosis.

Alternatives

We do not have alternatives for ジオスミン since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

ジオスミン is Diosmin in Japanese.

Is written in other languages:

Tradenames

Main tradenames from several countries containing ジオスミン in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 58 %
Molecular weight 609 daltons
VD 1 l/Kg
T1/2 11 hours

References

  1. Martinez-Zapata MJ, Vernooij RW, Uriona Tuma SM, Stein AT, Moreno RM, Vargas E, Capellà D, Bonfill Cosp X. Phlebotonics for venous insufficiency. Cochrane Database Syst Rev. 2016 Abstract
  2. Song BJ, Jouni ZE, Ferruzzi MG. Assessment of phytochemical content in human milk during different stages of lactation. Nutrition. 2013 Abstract Full text (link to original source) Full text (in our servers)
  3. Diosmina. Ficha técnica. 2012 Full text (in our servers)
  4. Daflon. Ficha técnica. 2012 Full text (in our servers)
  5. DGF. Dirección General de Farmacia. Servicio Canario de la Salud. Listado de fármacos considerados de Utilidad terapéutica Baja (UTB). 2011 Full text (in our servers)
  6. Cova D, De Angelis L, Giavarini F, Palladini G, Perego R. Pharmacokinetics and metabolism of oral diosmin in healthy volunteers. Int J Clin Pharmacol Ther Toxicol. 1992 Abstract

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