Last update: Dec. 13, 2019

Tripotassium Citrate

Very Low Risk for breastfeeding


Safe. Compatible.
Not risky for breastfeeding or infant.

It is used orally and intravenously to alkalize urine in the treatment of renal lithiasis and tubular acidosis.
After absorption, it is metabolized to bicarbonate. It has very low toxicity at the usual therapeutic doses (AEMPS 2012).
It is also used as a food additive (E 332) to reduce acidity.

Since the last update we have not found published data on its excretion in breastmilk.

Potassium is an ion present in breastmilk (Allen 1991) at a concentration 6 to 7 times greater than that of plasma: 18.3 ± 5.7 mEq/L. Like other monovalent ions, it freely enters and exits milk, inversely to the concentration of lactose (Lawrence 2016 p119). In the body, it is found mostly within cells, with a plasma concentration within specific limits (3.5 to 5.5 mEq/L).

Experts consider it compatible with breastfeeding (Briggs 2018).

Only in rare cases of maternal disease with high concentration of potassium in maternal blood (hyperkalaemia), can it increase its concentration in breastmilk, in which case possible gastrointestinal disorders and elevated plasma levels should be monitored in the infant.


See below the information of this related product:

Alternatives

We do not have alternatives for Tripotassium Citrate since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Tripotassium Citrate is also known as Potassium Citrate.


Tripotassium Citrate in other languages or writings:

Groups

Tripotassium Citrate belongs to these groups or families:

Tradenames

Main tradenames from several countries containing Tripotassium Citrate in its composition:

Pharmacokinetics

Variable Value Unit
Molecular weight 306 daltons

References

  1. Briggs GG, Freeman RK, Towers CV, Forinash AB. Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk. Wolters Kluwer Health. 11th edition (acces on line) 2017
  2. Lawrence RA, Lawrence RM. Breastfeeding. A guide for the medical profession. Eighth Edition. Philadelphia: Elsevier; 2016
  3. AEMPS. Citrato de potasio. Ficha técnica. 2012 Full text (in our servers)
  4. Mission Ph.C. Potassium Citrate. Drug Summary. 2010 Full text (in our servers)
  5. Allen JC, Keller RP, Archer P, Neville MC. Studies in human lactation: milk composition and daily secretion rates of macronutrients in the first year of lactation. Am J Clin Nutr. 1991 Abstract

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