Last update: July 31, 2018
Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.
Trandolapril and its active metabolite trandolaprilat are angiotensin converting enzyme inhibitors (ACEI) used in the treatment of hypertension and myocardial infarction.
Oral administration every 12 - 24 hours.
Since the last update we have not found published data on its excretion in breastmilk.
Other compounds from the same group (ACEI) are not excreted in breastmilk in significant amounts, but until there is more information about this drug in relation to breastfeeding, safer known alternatives are preferable (Anderson 2018, Hale 2017 p946).
Due to its possible renal toxicity in preterm infants, it is preferable to avoid its use during the neonatal period in case of prematurity. (Serrano 2015).
The protective role of breastfeeding against maternal hypertension has been proven (Park 2018).
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.
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