Last update: June 1, 2019

Tetracaine

Very Low Risk for breastfeeding


Safe. Compatible.
Not risky for breastfeeding or infant.

Anesthetic drugs for topical use, both dermatological and odontological, have almost nil absorption when properly used. Do not apply on breast. Otherwise, do it after having nursed, and cleanse it thoroughly with water before next feeding.

Alternatives

We do not have alternatives for Tetracaine since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Tetracaine is also known as


Tetracaine in other languages or writings:

Tradenames

Main tradenames from several countries containing Tetracaine in its composition:

Pharmacokinetics

Variable Value Unit
Bioavailability (Derma: 15) %
Molecular weight 264 daltons
Protein Binding 75 %
pKa 8,5 -
T1/2 1,25 hours

References

  1. Briggs GG, Freeman RK, Towers CV, Forinash AB. Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk. Wolters Kluwer Health. 11th edition (acces on line) 2017
  2. AEMPS-Braun. Tetracaína. Ficha técnica. 2014 Full text (in our servers)
  3. Galderma. LIdocaine & Tetracaine (Pliagis). Drug Summary. 2012 Full text (in our servers)
  4. Concin N, Hofstetter G, Plattner B, Tomovski C, Fiselier K, Gerritzen K, Fessler S, Windbichler G, Zeimet A, Ulmer H, Siegl H, Rieger K, Concin H, Grob K. Mineral oil paraffins in human body fat and milk. Food Chem Toxicol. 2008 Abstract
  5. Ogden L, Love G, Basta S. Systemic exposure to lidocaine and tetracaine is low after an application of a lidocaine 7%-tetracaine 7% peel in adults. Int J Dermatol. 2008 Jan;47(1):87-90. Abstract
  6. Schaefer C, Peters P, Miller RK. Drugs During Pregnancy and Lactation. Treatment options and risk assessment. Elsevier, second edition. London. 2007
  7. Noti A, Grob K, Biedermann M, Deiss U, Brüschweiler BJ. Exposure of babies to C15-C45 mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003 Abstract
  8. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Full text (link to original source) Full text (in our servers)
  9. Terndrup TE, Walls HC, Mariani PJ, Gavula DP, Madden CM, Cantor RM. Plasma cocaine and tetracaine levels following application of topical anesthesia in children. Ann Emerg Med. 1992 Feb;21(2):162-6. Abstract
  10. Mazumdar B, Tomlinson AA, Faulder GC. Preliminary study to assay plasma amethocaine concentrations after topical application of a new local anaesthetic cream containing amethocaine. Br J Anaesth. 1991 Oct;67(4):432-6. Abstract

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e-lactancia is a resource recommended by Instituto de Salud Infantil, Grecia-Institute of Child's Health in Greece

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