Last update: Feb. 20, 2018

Sodium Citrate

Very Low Risk for breastfeeding


Compatible.
Not risky for breastfeeding or infant.

Sodium salt of citric acid.
It is used rectally in enemas as it acts as an osmotic laxative and in bladder irrigations to dissolve clots. It has the alkalizing properties of urine, neutralizing gastric pH and is an anticoagulant.

Since the last update, we have not found published data on its excretion in breast milk.

Given the small amounts and route of administration, systemic absorption is practically nil (AEMPS 2013), so no significant excretion in breast milk is expected.

If absorbed, it is metabolized to bicarbonate.

Both sodium and bicarbonate are normal components of the body and are found in breastmilk at concentrations which are different to plasma (Allen 1991).

Alternatives

We do not have alternatives for Sodium Citrate since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Sodium Citrate is also known as


Sodium Citrate in other languages or writings:

Groups

Sodium Citrate belongs to these groups or families:

Tradenames

Main tradenames from several countries containing Sodium Citrate in its composition:

  • Clisteran™. Contains other elements than Sodium Citrate in its composition
  • Micralax™. Contains other elements than Sodium Citrate in its composition
  • Microlax ™. Contains other elements than Sodium Citrate in its composition
  • Pazbronquial™. Contains other elements than Sodium Citrate in its composition

Pharmacokinetics

Variable Value Unit
Molecular weight 294 daltons
VD 0,27 - 0,55 l/Kg
Tmax 1,6 - 2,2 hours
T1/2 0,3 - 0,9 hours

References

  1. AEMPS. Micralax. Ficha técnica. 2013 Full text (in our servers)
  2. Allen JC, Keller RP, Archer P, Neville MC. Studies in human lactation: milk composition and daily secretion rates of macronutrients in the first year of lactation. Am J Clin Nutr. 1991 Abstract

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