Last update: Dec. 18, 2015

Smoke Weed

Very High Risk for breastfeeding


Very unsafe. Contraindicated.
Use of an alternative or cessation of breastfeeding.

Delta-9-tetrahydrocannabinol (THC) is a liposoluble metabolite that accumulates in fat tissue and may reach a concentration in the human milk that would be as high as 8 times of plasma level.

It has been shown to induce hypotonia, poor suction, sedation and psychomotor delay in one-year-old children who were exposed to cannabis through breastfeeding.

THC has been detected in the infant's urine for three weeks after exposition.

Mean head circumference may be lower than that of non-exposed infants.

A higher risk for Sudden Unexpected Death of Infancy has been linked to homes of consumers.

In spite of reduction of Prolactin level, no decrease in milk production has been observed.

The deleterious effect on judgment and behavior seen in individuals who use Cannabis may interfere with ability of women for motherhood and will pose a higher risk for life-threatening and harm to health.

Alternatives

We do not have alternatives for Smoke Weed.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Smoke Weed is also known as Cannabis. Here it is a list of alternative known names::


Group

Smoke Weed belongs to this group or family:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 10 - 35 %
Molecular weight 314 daltons
Protein Binding 99 %
VD 4 - 19 l/Kg
Tmax 0,5 - 2 hours
T1/2 28 - 56 hours
M/P ratio 8 -

References

  1. UNICEF UK. Caring for your baby at night. A guide for parents. 2018 Full text (link to original source) Full text (in our servers)
  2. Ball H, Blair PS. (For UNICEF UK). Caring for your baby at night. Health professional´s guide. 2017 Full text (link to original source) Full text (in our servers)
  3. Reece-Stremtan S, Marinelli KA. ABM Clinical Protocol #21: Guidelines for Breastfeeding and Substance Use or Substance Use Disorder, Revised 2015. Breastfeed Med. 2015 Abstract Full text (link to original source) Full text (in our servers)
  4. ABM Protocolo clínico de la ABM n.º 21: Pautas para la lactancia y el consumo de sustancias o trastorno por consumo de sustancias, revisado en 2015. Breastfeed Med. 2015 Full text (link to original source) Full text (in our servers)
  5. Michael O. Schroeder. Hazy Advice: Should Moms Who Smoke Weed Continue to Breast-feed? U.S. News & World Report. 12.01. 2015 Full text (link to original source) Full text (in our servers)
  6. Yurcheshen M, Seehuus M, Pigeon W. Updates on Nutraceutical Sleep Therapeutics and Investigational Research. Evid Based Complement Alternat Med. 2015 Abstract Full text (link to original source) Full text (in our servers)
  7. Jaques SC, Kingsbury A, Henshcke P, Chomchai C, Clews S, Falconer J, Abdel-Latif ME, Feller JM, Oei JL. Cannabis, the pregnant woman and her child: weeding out the myths. J Perinatol. 2014 Abstract
  8. UNICEF UK. Statement on co-sleeping following publication of new NICE postnatal guidance. Infosheet. 2014 Full text (link to original source) Full text (in our servers)
  9. Sachs HC; Committee On Drugs. The transfer of drugs and therapeutics into human breast milk: an update on selected topics. Pediatrics. 2013 Sep;132(3):e796-809. Abstract Full text (link to original source) Full text (in our servers)
  10. Rowe H, Baker T, Hale TW. Maternal medication, drug use, and breastfeeding. Pediatr Clin North Am. 2013 Feb;60(1):275-94. Abstract
  11. UNICEF UK Baby Friendly Initiative statement on Bed-sharing when parents do not smoke: is there a risk of SIDS? An individual level analysis of five major case-control studies. 2013 Full text (link to original source) Full text (in our servers)
  12. Hill M, Reed K. Pregnancy, breast-feeding, and marijuana: a review article. Obstet Gynecol Surv. 2013 Abstract
  13. L.Landa Rivera, M.Díaz-Gómez, A.Gómez Papi, J.M.Paricio Talayero, C.Pallás Alonso, M.T.Hernández Aguilar, J.Aguayo Maldonado, J.M.Arena Ansotegui, S.Ares Segura, A.Jiménez Moya, J.J.Lasarte Velillas, J.Martín Calama, M.D.Romero Escós. El colecho favorece la práctica de la lactancia materna y no aumenta el riesgo de muerte súbita del lactante. Dormir con los padres. Rev Pediatr Aten Primaria. 14:53-60 2012 Full text (link to original source) Full text (in our servers)
  14. Sharma P, Murthy P, Bharath MM. Chemistry, metabolism, and toxicology of cannabis: clinical implications. Iran J Psychiatry. 2012 Abstract Full text (link to original source) Full text (in our servers)
  15. Tkaczyk M, Florek E, Piekoszewski W. [Marihuana and cannobinoids as medicaments]. Przegl Lek. 2012 Abstract
  16. Wong S, Ordean A, Kahan M; Maternal Fetal Medicine Committee; Family Physicians Advisory Committee; Medico-Legal Committee; Society of Obstetricians and Gynaecologists of Canada. Substance use in pregnancy. J Obstet Gynaecol Can. 2011 Abstract Full text (in our servers)
  17. [No authors listed] Adverse effects of cannabis. Prescrire Int. 2011 Abstract
  18. Ranganathan M, Braley G, Pittman B, Cooper T, Perry E, Krystal J, D'Souza DC. The effects of cannabinoids on serum cortisol and prolactin in humans. Psychopharmacology (Berl). 2009 Abstract Full text (link to original source) Full text (in our servers)
  19. Hall W, Degenhardt L. Adverse health effects of non-medical cannabis use. Lancet. 2009 Abstract
  20. Garry A, Rigourd V, Amirouche A, Fauroux V, Aubry S, Serreau R. Cannabis and breastfeeding. J Toxicol. 2009 Abstract Full text (link to original source) Full text (in our servers)
  21. Campolongo P, Trezza V, Palmery M, Trabace L, Cuomo V. Developmental exposure to cannabinoids causes subtle and enduring neurofunctional alterations. Int Rev Neurobiol. 2009 Abstract
  22. ABM - Comité de protocolos de la Academia médica de lactancia materna (Academy of Breastfeeding Medicine). Protocolo Clínico de la ABM #6: Lineamientos sobre la práctica de dormir al bebé junto con la madre y la lactancia materna Revisión, marzo de 2008. Breastfeeding Medicine 2008 Full text (link to original source) Full text (in our servers)
  23. ABM - The Academy of Breastfeeding Medicine Protocol Committee. ABM Clinical Protocol #6: Guideline on Co-Sleeping and Breastfeeding. Breastfeeding Medicine 2008 Abstract Full text (link to original source) Full text (in our servers)
  24. Moore TH, Zammit S, Lingford-Hughes A, Barnes TR, Jones PB, Burke M, Lewis G. Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review. Lancet. 2007 Abstract
  25. UNICEF UK. Compartiendo la cama con tu bebé. Guía para madres que amamantan. Folleto 2006 Full text (in our servers)
  26. Van der Meersch H, Verschuere AP, Bottriaux F. [Medicinal cannabis]. J Pharm Belg. 2006 Abstract
  27. Djulus J, Moretti M, Koren G. Marijuana use and breastfeeding. Can Fam Physician. 2005 Abstract Full text (link to original source) Full text (in our servers)
  28. Fernández-Ruiz J, Gómez M, Hernández M, de Miguel R, Ramos JA. Cannabinoids and gene expression during brain development. Neurotox Res. 2004 Abstract
  29. Klonoff-Cohen H, Lam-Kruglick P. Maternal and paternal recreational drug use and sudden infant death syndrome. Arch Pediatr Adolesc Med. 2001 Abstract
  30. Moretti ME, Lee A, Ito S. Which drugs are contraindicated during breastfeeding? Practice guidelines. Can Fam Physician. 2000 Sep;46:1753-7. Review. Abstract Full text (link to original source) Full text (in our servers)
  31. Fried PA, Watkinson B, Gray R. Growth from birth to early adolescence in offspring prenatally exposed to cigarettes and marijuana. Neurotoxicol Teratol. 1999 Abstract
  32. Liston J. Breastfeeding and the use of recreational drugs--alcohol, caffeine, nicotine and marijuana. Breastfeed Rev. 1998 Abstract
  33. Astley SJ, Little RE. Maternal marijuana use during lactation and infant development at one year. Neurotoxicol Teratol. 1990 Abstract
  34. Mendelson JH, Mello NK, Ellingboe J. Acute effects of marihuana smoking on prolactin levels in human females. J Pharmacol Exp Ther. 1985 Abstract
  35. Tennes K, Avitable N, Blackard C, Boyles C, Hassoun B, Holmes L, Kreye M. Marijuana: prenatal and postnatal exposure in the human. NIDA Res Monogr. 1985 Abstract Full text (link to original source) Full text (in our servers)
  36. Perez-Reyes M, Wall ME. Presence of delta9-tetrahydrocannabinol in human milk. N Engl J Med. 1982 Abstract

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