Last update: July 20, 2017

Probiotics

Very Low Risk for breastfeeding


Safe. Compatible.
Not risky for breastfeeding or infant.

The administration of probiotics to the mother may partially alter the composition of milk: changes have been shown in the lipid profile, IgA levels (increase or decrease depending on studies) and in other immunological factors as citoquinasTGF-β1 and TGF-β2. The impact and importance of this are not well known.

Research on the use of probiotics for treatment of various pathological conditions, necrotizing enterocolitis, asthma, atopic dermatitis, colicky pain, mastitis, breast pain, vaginitis, gastroenteritis (see specific sheet of Saccharomyces boulardii) and inflammatory bowel disease, among others, is very promising, but so far with very modest results and the lack of significant scientific level 1 evidence based.

Probiotics seem to be safe, except in cases of severe maternal immune disease or severe maternal intestinal compromise. They have been administered to preterm infants to prevent necrotizing enterocolitis but evidence that orally administered can get into the milk is lacking.

Breast milk is an important source of probiotics and prebiotics. Contains numerous species of saprophytic bacteria (Staphylococcus epidermidis, Streptococcus salivarius, Enterococci , Lactobacilli) with immuno-modulatory and anti-inflammatory properties that inhibit the growth of pathogenic bacteria (Staphylococcus aureus). Also, contains oligosaccharides that promote the growth of these commensal bacteria in the infant gut .

Breastfeeding plays a fundamental role in the colonization of the newborn gut. During the first years of life intestinal flora of infants varies according to whether or not breastfed.


See below the information of these related products:

Alternatives

We do not have alternatives for Probiotics since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Probiotics is also known as


Group

Probiotics belongs to this group or family:

Tradenames

Main tradenames from several countries containing Probiotics in its composition:

References

  1. Amir LH, Griffin L, Cullinane M, Garland SM. Probiotics and mastitis: evidence-based marketing? Int Breastfeed J. 2016 Abstract Full text (link to original source) Full text (in our servers)
  2. Espínola-Docio B, Costa-Romero M, Díaz-Gómez NM, Paricio-Talayero JM; Comité de Lactancia Materna, Asociación Española de Pediatría.. Mastitis. Puesta al día. [Mastitis update.] Arch Argent Pediatr. 2016 Abstract Full text (link to original source) Full text (in our servers)
  3. Espínola-Docio B, Costa-Romero M, Díaz-Gómez NM, Paricio-Talayero JM; Comité de Lactancia Materna, Asociación Española de Pediatría.. [Mastitis update.] Arch Argent Pediatr. 2016 Abstract
  4. Baeza C. Dolor en la mama lactante: claves etiológicas y manejo clínico (I). Monografías Clínicas en Lactancia Materna. Madrid: Centro Raíces 2015, p.3-13. 2015 Full text (link to original source) Full text (in our servers)
  5. Kubota T, Shimojo N, Nonaka K, Yamashita M, Ohara O, Igoshi Y, Ozawa N, Nakano T, Morita Y, Inoue Y, Arima T, Chiba K, Nakamura Y, Ikegami S, Masuda K, Suzuki S, Kohno Y. Prebiotic consumption in pregnant and lactating women increases IL-27 expression in human milk. Br J Nutr. 2014 Abstract
  6. Fernández L, Arroyo R, Espinosa I, Marín M, Jiménez E, Rodríguez JM. Probiotics for human lactational mastitis. Benef Microbes. 2014 Abstract
  7. Benor S, Marom R, Ben Tov A, Armoni Domany K, Zaidenberg-Israeli G, Dollberg S. Probiotic supplementation in mothers of very low birth weight infants. Am J Perinatol. 2014 Abstract
  8. Amir LH. ABM Clinical Protocol #4: Mastitis, Revised March 2014. Breastfeed Med. 2014 Abstract Full text (link to original source) Full text (in our servers)
  9. Walker WA. Initial intestinal colonization in the human infant and immune homeostasis. Ann Nutr Metab. 2013 Abstract Full text (link to original source) Full text (in our servers)
  10. Weng M, Walker WA. The role of gut microbiota in programming the immune phenotype. J Dev Orig Health Dis. 2013 Abstract Full text (link to original source) Full text (in our servers)
  11. Nikniaz L, Ostadrahimi A, Mahdavi R, Hejazi MA, Salekdeh GH. Effects of synbiotic supplementation on breast milk levels of IgA, TGF-β1, and TGF-β2. J Hum Lact. 2013 Abstract
  12. Benor S, Marom R, Tov AB, Domany KA, Zaidenberg-Israeli G, Dollberg S. Probiotic Supplementation in Mothers of Very Low Birth Weight Infants. Am J Perinatol. 2013 Abstract
  13. Wickens K, Stanley TV, Mitchell EA, Barthow C, Fitzharris P, Purdie G, Siebers R, Black PN, Crane J. Early supplementation with Lactobacillus rhamnosus HN001 reduces eczema prevalence to 6 years: does it also reduce atopic sensitization? Clin Exp Allergy. 2013 Abstract
  14. Martín V, Maldonado-Barragán A, Moles L, Rodriguez-Baños M, Campo RD, Fernández L, Rodríguez JM, Jiménez E. Sharing of bacterial strains between breast milk and infant feces. J Hum Lact. 2012 Abstract Full text (link to original source) Full text (in our servers)
  15. Thum C, Cookson AL, Otter DE, McNabb WC, Hodgkinson AJ, Dyer J, Roy NC. Can nutritional modulation of maternal intestinal microbiota influence the development of the infant gastrointestinal tract? J Nutr. 2012 Abstract Full text (link to original source) Full text (in our servers)
  16. Rautava S, Kainonen E, Salminen S, Isolauri E. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012 Abstract Full text (link to original source) Full text (in our servers)
  17. Weber TK, Polanco I. Gastrointestinal microbiota and some children diseases: a review. Gastroenterol Res Pract. 2012 Abstract Full text (link to original source) Full text (in our servers)
  18. Hoppu U, Isolauri E, Laakso P, Matomäki J, Laitinen K. Probiotics and dietary counselling targeting maternal dietary fat intake modifies breast milk fatty acids and cytokines. Eur J Nutr. 2012 Abstract
  19. Luoto R, Laitinen K, Nermes M, Isolauri E. Impact of maternal probiotic-supplemented dietary counseling during pregnancy on colostrum adiponectin concentration: a prospective, randomized, placebo-controlled study. Early Hum Dev. 2012 Abstract
  20. Grześkowiak Ł, Grönlund MM, Beckmann C, Salminen S, von Berg A, Isolauri E. The impact of perinatal probiotic intervention on gut microbiota: double-blind placebo-controlled trials in Finland and Germany. Anaerobe. 2012 Abstract
  21. Boyle RJ, Ismail IH, Kivivuori S, Licciardi PV, Robins-Browne RM, Mah LJ, Axelrad C, Moore S, Donath S, Carlin JB, Lahtinen SJ, Tang ML. Lactobacillus GG treatment during pregnancy for the prevention of eczema: a randomized controlled trial. Allergy. 2011 Abstract Full text (link to original source) Full text (in our servers)
  22. Elias J, Bozzo P, Einarson A. Are probiotics safe for use during pregnancy and lactation? Can Fam Physician. 2011 Abstract Full text (link to original source) Full text (in our servers)
  23. Sanz Y. Gut microbiota and probiotics in maternal and infant health. Am J Clin Nutr. 2011 Abstract Full text (link to original source) Full text (in our servers)
  24. Vandenplas Y, Veereman-Wauters G, De Greef E, Peeters S, Casteels A, Mahler T, Devreker T, Hauser B. Probiotics and prebiotics in prevention and treatment of diseases in infants and children. J Pediatr (Rio J). 2011 Abstract Full text (link to original source) Full text (in our servers)
  25. Foisy M, Boyle RJ, Chalmers JR, Simpson EL, Williams HC. Overview of Reviews The prevention of eczema in infants and children: an overview of Cochrane and non-Cochrane reviews. Evid Based Child Health. 2011 Abstract Full text (link to original source) Full text (in our servers)
  26. Arroyo R, Martín V, Maldonado A, Jiménez E, Fernández L, Rodríguez JM. Treatment of infectious mastitis during lactation: antibiotics versus oral administration of Lactobacilli isolated from breast milk. Clin Infect Dis. 2010 Abstract Full text (link to original source) Full text (in our servers)
  27. Dotterud CK, Storrø O, Johnsen R, Oien T. Probiotics in pregnant women to prevent allergic disease: a randomized, double-blind trial. Br J Dermatol. 2010 Abstract Full text (link to original source) Full text (in our servers)
  28. Thomas DW, Greer FR; American Academy of Pediatrics Committee on Nutrition; American Academy of Pediatrics Section on Gastroenterology, Hepatology, and Nutrition. Probiotics and prebiotics in pediatrics. Pediatrics. 2010 Abstract Full text (link to original source) Full text (in our servers)
  29. Thomas DW, Greer FR; American Academy of Pediatrics Committee on Nutrition.; American Academy of Pediatrics Section on Gastroenterology, Hepatology, and Nutrition.. Probiotics and prebiotics in pediatrics. Pediatrics. 2010 Abstract
  30. Lahtinen SJ, Boyle RJ, Kivivuori S, Oppedisano F, Smith KR, Robins-Browne R, Salminen SJ, Tang ML. Prenatal probiotic administration can influence Bifidobacterium microbiota development in infants at high risk of allergy. J Allergy Clin Immunol. 2009 Abstract Full text (link to original source) Full text (in our servers)
  31. Shafai T. Routine supplement of prebiotics and probiotics to newborn infants is not recommended. Pediatrics. 2009 Abstract Full text (link to original source) Full text (in our servers)
  32. Abrahamsson TR, Sinkiewicz G, Jakobsson T, Fredrikson M, Björkstén B. Probiotic lactobacilli in breast milk and infant stool in relation to oral intake during the first year of life. J Pediatr Gastroenterol Nutr. 2009 Abstract
  33. Snydman DR. The safety of probiotics. Clin Infect Dis. 2008 Abstract Full text (link to original source) Full text (in our servers)
  34. Jiménez E, Fernández L, Maldonado A, Martín R, Olivares M, Xaus J, Rodríguez JM. Oral administration of Lactobacillus strains isolated from breast milk as an alternative for the treatment of infectious mastitis during lactation. Appl Environ Microbiol. 2008 Abstract Full text (link to original source) Full text (in our servers)
  35. Prescott SL, Wickens K, Westcott L, Jung W, Currie H, Black PN, Stanley TV, Mitchell EA, Fitzharris P, Siebers R, Wu L, Crane J; Probiotic Study Group. Supplementation with Lactobacillus rhamnosus or Bifidobacterium lactis probiotics in pregnancy increases cord blood interferon-gamma and breast milk transforming growth factor-beta and immunoglobin A detection. Clin Exp Allergy. 2008 Abstract
  36. Böttcher MF, Abrahamsson TR, Fredriksson M, Jakobsson T, Björkstén B. Low breast milk TGF-beta2 is induced by Lactobacillus reuteri supplementation and associates with reduced risk of sensitization during infancy. Pediatr Allergy Immunol. 2008 Abstract
  37. Prescott SL, Wickens K, Westcott L, Jung W, Currie H, Black PN, Stanley TV, Mitchell EA, Fitzharris P, Siebers R, Wu L, Crane J; Probiotic Study Group.. Supplementation with Lactobacillus rhamnosus or Bifidobacterium lactis probiotics in pregnancy increases cord blood interferon-gamma and breast milk transforming growth factor-beta and immunoglobin A detection. Clin Exp Allergy. 2008 Abstract
  38. Boyle RJ, Robins-Browne RM, Tang ML. Probiotic use in clinical practice: what are the risks? Am J Clin Nutr. 2006 Abstract Full text (link to original source) Full text (in our servers)
  39. Penders J, Thijs C, Vink C, Stelma FF, Snijders B, Kummeling I, van den Brandt PA, Stobberingh EE. Factors influencing the composition of the intestinal microbiota in early infancy. Pediatrics. 2006 Abstract Full text (link to original source) Full text (in our servers)
  40. Gueimonde M, Sakata S, Kalliomäki M, Isolauri E, Benno Y, Salminen S. Effect of maternal consumption of lactobacillus GG on transfer and establishment of fecal bifidobacterial microbiota in neonates. J Pediatr Gastroenterol Nutr. 2006 Abstract
  41. Rinne M, Kalliomaki M, Arvilommi H, Salminen S, Isolauri E. Effect of probiotics and breastfeeding on the bifidobacterium and lactobacillus/enterococcus microbiota and humoral immune responses. J Pediatr. 2005 Abstract
  42. Borriello SP, Hammes WP, Holzapfel W, Marteau P, Schrezenmeir J, Vaara M, Valtonen V. Safety of probiotics that contain lactobacilli or bifidobacteria. Clin Infect Dis. 2003 Abstract Full text (link to original source) Full text (in our servers)
  43. Heikkilä MP, Saris PE. Inhibition of Staphylococcus aureus by the commensal bacteria of human milk. J Appl Microbiol. 2003 Abstract Full text (link to original source) Full text (in our servers)
  44. Rautava S, Kalliomäki M, Isolauri E. Probiotics during pregnancy and breast-feeding might confer immunomodulatory protection against atopic disease in the infant. J Allergy Clin Immunol. 2002 Abstract Full text (link to original source) Full text (in our servers)
  45. Novak FR, Almeida JA, Silva GO, Borba LM. [Human colostrum: a natural source of probiotics?] J Pediatr (Rio J). 2001 Abstract Full text (link to original source) Full text (in our servers)

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