Last update: Jan. 20, 2015

Papain

Low Risk for breastfeeding


Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.

Proteolytic enzyme from Carica papaya. It is used in food industry as a meat softener. Doubtfully effective as anti-inflammatory and GI tract medication.

Alternatives

We do not have alternatives for Papain.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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José María Paricio, founder of e-lactancia.
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Other names

Papain is also known as


Groups

Papain belongs to these groups or families:

Tradenames

Main tradenames from several countries containing Papain in its composition:

List of 17 tradenames

Pharmacokinetics

Variable Value Unit
Molecular weight 23.000 daltons

References

  1. Rosenthal AP, Blønd MB. [The enzyme papain in industry and food causes allergic sensitization]. Ugeskr Laeger. 2008 Abstract
  2. Lee J, Anderson R. Best evidence topic report. Proteolytic enzymes for oesophageal meat impaction. Emerg Med J. 2005 Abstract Full text (link to original source) Full text (in our servers)
  3. Ncube TN, Greiner T, Malaba LC, Gebre-Medhin M. Supplementing lactating women with puréed papaya and grated carrots improved vitamin A status in a placebo-controlled trial. J Nutr. 2001 Abstract Full text (link to original source) Full text (in our servers)
  4. Kinlay JR, O'Connell DL, Kinlay S. Risk factors for mastitis in breastfeeding women: results of a prospective cohort study. Aust N Z J Public Health. 2001 Abstract
  5. Maini S, Rudralingam M, Zeitoun H, Osbourne JE. Aspiration pneumonitis following papain enzyme treatment for oesophageal meat impaction. J Laryngol Otol. 2001 Abstract
  6. Bourdy G, Walter A. Maternity and medicinal plants in Vanuatu. I. The cycle of reproduction. J Ethnopharmacol. 1992 Abstract

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