Last update: May 11, 2019
Minimal risk for breastfeeding and infant.
Short-acting benzodiazepine with anxiolytic effect. Used in anxiety states.
Final active metabolite of diazepam.
Oral administration 3 times a day.
Excreted into breast milk in non-significant level (Dusci 1990, Wretlind 1987).
Plasma levels of oxazepam in the infant were between 10 and 30 times lower than the maternal ones (Dusci 1990).
No harm effects on breastfed infants have been shown (Kelly 2012, Dusci 1990)..
The occasional use and low doses of benzodiazepines are compatible with breastfeeding (Kelly 2012, Rubin 2004, Iqbal 2002, Hägg 2000, McElhatton 1994, Lee 1993, Kanto 1982).
It is advisable to choose a short-acting benzodiazepine and minimal effective dose as possible (Rowe 2013), especially in the neonatal period and in case of prematurity because they can accumulate in the infant during chronic use (Sachs 2013).
It is advisable to monitor drowsiness and adequate feeding of the infant.
It is not recommended to share a bed (co-sleeping, bed-sharing) with the baby if this drug is being taken, due to increased risk of asphyxia or sudden infant death (UNICEF UK 2018, 2017, 2014 and 2013, Landa 2012, ABM 2008, UNICEF UK 2006).
We do not have alternatives for Oxazepam since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
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