Last update: May 31, 2019
Not risky for breastfeeding or infant.
Aminoglycoside antibiotic which is used in creams, eye drops, and otologic preparations for topical use, and, also orally used for intestinal disinfection.
Since the last update we have not found any published data on its excretion in breast milk.
The small dose and poor plasma uptake of most topical nasal, ophthalmologic, otological and dermatological preparations make it very unlikely that significant amounts will pass into breast milk (Leachman 2006, Niebyl 1992).
Neomycin, like the rest of aminoglycosides, has very low oral bioavailability (Briggs 2017, Chin 2001, Fulton 1992), which makes it difficult for the infant to pass to plasma from ingested breast milk, except in premature infants and the immediate neonatal period in which it can have greater intestinal permeability (Nelson 1972).
It is advisable to avoid the application to the nipple of creams, gels and other topical products containing paraffin (mineral oil) so that the infant does not absorb them (Concin 2008, Noti 2003)
In case of use of Neomycin on the nipple, let it be done after the feed and wipe it out any excess of cream before the next feed.
Be aware of false negative results of bacterial cultures obtained from febrile infants whose mothers are on antibiotics, as well as the possibility of gastroenteritis due to altered intestinal flora (Arbex 2010, Ito 1993).
List of WHO essential medicines: compatible with breastfeeding (WHO / UNICEF 2002).
We do not have alternatives for Neomycin since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.
e-lactancia is a resource recommended by Confederación Nacional de Pediatría (CONAPEME) from Mexico
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM