Last update: Nov. 27, 2016

Magnesium Oxide

Very Low Risk for breastfeeding


Safe. Compatible.
Not risky for breastfeeding or infant.

Ingested Magnesium does not concentrate into breast milk.

Naturally occurring, the mean Magnesium concentration in the milk is 31 mg/L (range 15 – 64 mg/L) and not affected by the ingestion of Magnesium.

Because of a low oral bioavailability the pass from the breast milk toward the infant's plasma is hampered, except in premature and newborn infants who may exhibit a higher intestinal absorption due to an increased permeability.

Avoid chronic or excessive use.

WHO Model List of Essential Medicines 2002: Magnesium oxide is compatible with breastfeeding.

Alternatives

We do not have alternatives for Magnesium Oxide since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Groups

Magnesium Oxide belongs to these groups or families:

Tradenames

Main tradenames from several countries containing Magnesium Oxide in its composition:

  • CitraFleet™. Contains other elements than Magnesium Oxide in its composition
  • Elevit™. Contains other elements than Magnesium Oxide in its composition
  • Multibionta Complex™. Contains other elements than Magnesium Oxide in its composition
  • Oblax A-1-1™. Contains other elements than Magnesium Oxide in its composition

Pharmacokinetics

Variable Value Unit
Bioavailability 10 - 30 %
Molecular weight 40 daltons

References

  1. Dabeka R, Fouquet A, Belisle S, Turcotte S. Lead, cadmium and aluminum in Canadian infant formulae, oral electrolytes and glucose solutions. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2011 Abstract
  2. Burrell SA, Exley C. There is (still) too much aluminium in infant formulas. BMC Pediatr. 2010 Abstract Full text (link to original source) Full text (in our servers)
  3. Mahadevan U, Kane S. American gastroenterological association institute technical review on the use of gastrointestinal medications in pregnancy. Gastroenterology. 2006 Jul;131(1):283-311. Review. Abstract Full text (link to original source) Full text (in our servers)
  4. Richter JE. Review article: the management of heartburn in pregnancy. Aliment Pharmacol Ther. 2005 Abstract Full text (in our servers)
  5. Rodríguez Rodríguez EM, Sanz Alaejos M, Díaz Romero C. [Concentrations of calcium, magnesium, sodium and potassium in human milk and infant formulas]. Arch Latinoam Nutr. 2002 Abstract
  6. Dórea JG. Magnesium in human milk. J Am Coll Nutr. 2000 Abstract
  7. Hagemann TM. Gastrointestinal medications and breastfeeding. J Hum Lact. 1998 Abstract
  8. Broussard CN, Richter JE. Treating gastro-oesophageal reflux disease during pregnancy and lactation: what are the safest therapy options? Drug Saf. 1998 Abstract
  9. Nagy E, Jobst K. The kinetics of aluminium-containing antacid absorption in man. Eur J Clin Chem Clin Biochem. 1994 Abstract
  10. Simmer K, Fudge A, Teubner J, James SL. Aluminum concentrations in infant formulae. J Paediatr Child Health. 1990 Abstract
  11. Lewis JH, Weingold AB. The use of gastrointestinal drugs during pregnancy and lactation. Am J Gastroenterol. 1985 Abstract
  12. Feeley RM, Eitenmiller RR, Jones JB Jr, Barnhart H. Calcium, phosphorus, and magnesium contents of human milk during early lactation. J Pediatr Gastroenterol Nutr. 1983 Abstract

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