Last update: Jan. 4, 2021
Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.
Levobunolol Hydrochloride in other languages or writings:
Levobunolol Hydrochloride belongs to this group or family:
Main tradenames from several countries containing Levobunolol Hydrochloride in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 80 | % |
Molecular weight | 328 | daltons |
VD | 5,5 | l/Kg |
pKa | 14,09 | - |
Tmax | 3 | hours |
T1/2 | 6 - 8 | hours |
Write to us at elactancia.org@gmail.com
e-lactancia is a resource recommended by La Liga de la Leche, España from Spain
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
It is a non-cardioselective beta blocker
It is used in the treatment of glaucoma and ocular hypertension,
Topical administration as eye drops, one drop every 12 to 24 hours.
Since the last update we have not found any published data on its excretion in breast milk.
Its pharmacokinetic characteristics (large volume of distribution and high pKA), make it very unlikely its excretion into breast milk in significant amounts.
Absorption should be minimized by closing the eye after instillation, applying pressure for 1 to 5 minutes with your finger on the tear duct at the inner corner of the eye and administering the dose immediately after nursing (Blumen 2020, Belkin 2020, Méndez 2012, Johnson 2001).
Until there is further published data on this drug in relation to breastfeeding, known safer alternatives may be preferable, especially during the neonatal period and in cases of prematurity.