Last update: Nov. 24, 2016

Lactase

Very Low Risk for breastfeeding


Safe. Compatible.
Minimal risk for breastfeeding and infant.

Enzyme which is composed by more than 1.000 amino acids that hydrolyzes Lactose into Glucose and Galactose. It is produced in larger quantity by intestinal cells of newborns and infants than older children and adults, in order to digest the milk sugar or Lactose. Depending on type of populations, only 30 to 70% of individuals can continue producing intestinal lactose in later ages.

At latest update information was not found on excretion into breast milk, but, because it's proteic nature it would be digested before absorption, all that along with a high molecular weight makes excretion intro breast milk highly unlikely.

In addition, it is not toxic since it has been used, with no effectiveness, for treatment of colicky pain in infants without side-effects reported.

Alternatives

We do not have alternatives for Lactase since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Tradenames

Main tradenames from several countries containing Lactase in its composition:

Pharmacokinetics

Variable Value Unit
Molecular weight 464.000 daltons

References

  1. Krüttli A, Bouwman A, Akgül G, Della Casa P, Rühli F, Warinner C. Ancient DNA analysis reveals high frequency of European lactase persistence allele (T-13910) in medieval central europe. PLoS One. 2014 Abstract
  2. [No authors listed] Management of infantile colic. Drug Ther Bull. 2013 Abstract
  3. Hall B, Chesters J, Robinson A. Infantile colic: a systematic review of medical and conventional therapies. J Paediatr Child Health. 2012 Abstract
  4. Critch J. Infantile colic: Is there a role for dietary interventions? Paediatr Child Health. 2011 Abstract
  5. Bersaglieri T, Sabeti PC, Patterson N, Vanderploeg T, Schaffner SF, Drake JA, Rhodes M, Reich DE, Hirschhorn JN. Genetic signatures of strong recent positive selection at the lactase gene. Am J Hum Genet. 2004 Abstract
  6. Royer P. Breast feeding and biological development. Acta Paediatr Scand. 1978 Abstract

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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine from United States of America

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