Last update: Aug. 25, 2019

Hypromellose

Very Low Risk for breastfeeding


Safe. Compatible.
Minimal risk for breastfeeding and infant.

A semisynthetic, inert and viscoelastic polymer with thickening, bioadhesive and solubility enhancing properties.
It is used as a pharmaceutical coating to modify its intestinal release and prolong its effect.
Used as a lubricant in the form of eye drops.

Since the last update we have not found published data on its excretion in breastmilk.

Since it is a derivative of cellulose, it is not absorbed either in the intestine or as an ophthalmological preparation (AEMPS 2014, MHRA 2009), so it is highly unlikely to appear in breastmilk. Its high molecular weight (Fukasawa 2004) makes its excretion in milk even less likely.

It is an inert product that is not metabolized and is devoid of toxicity, lacking systemic side effects (AEMPS 2014).

Alternatives

We do not have alternatives for Hypromellose since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Group

Hypromellose belongs to this group or family:

Tradenames

Main tradenames from several countries containing Hypromellose in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 0 %
Molecular weight 13.000 - 20.000 daltons

References

  1. AEMPS-Stada. Hipromelosa. Ficha técnica. 2014 Full text (in our servers)
  2. MHRA. Hypromellose. Drug Summary. 2009 Full text (in our servers)
  3. Fukasawa M, Obara S. Molecular weight determination of hypromellose acetate succinate (HPMCAS) using size exclusion chromatography with a multi-angle laser light scattering detector. Chem Pharm Bull (Tokyo). 2004 Abstract

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