Last update: May 13, 2018
Minimal risk for breastfeeding and infant.
A uric acid derivative that is found in body fluids (urine, amniotic fluid, saliva) of certain animals (cows, snails) and plants (comfrey).
Uric acid is the final product from the degradation of purines in humans and primates that do not possess an enzyme which degrades uric acid to allantoin in other mammals and non-mammals.
Purines are very abundant in meats, entrails, fish, seafood and beer.
Allantoin is used topically as a cosmetic and in oral hygiene products. It has healing properties (PubChem 2017 7.1)
Since the last update date we have not found published data on its excretion in breastmilk.
The low plasma absorption of most topical dermatological preparations makes it unlikely that it will transfer to breast milk in significant amounts.
There is no known toxicity (Akema 2012).
Do not apply on the chest in order to prevent the infant from ingesting it; if necessary, apply after breastfeeding and clean well with water before the next feed.
We do not have alternatives for Glyoxyldiureide since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.
e-lactancia is a resource recommended by Instituto de Salud Infantil, Grecia-Institute of Child's Health in Greece
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM