Last update: June 17, 2017

Fenticonazole Nitrate

Very Low Risk for breastfeeding


Safe. Compatible.
Not risky for breastfeeding or infant.

A topical anti-fungal treatment from the imidazole family applied to the skin or vaginally.

Negligible systemic absorption through the skin (Effik 2010) or vaginal mucosa (Novelli 1991) make it very unlikely that significant amounts pass into breast milk.

Do not apply on nipple-areola or alternatively clean before breastfeeding.

It is advisable to avoid the application to the nipple of creams, gels and other topical products containing paraffin (mineral oil) so that the infant does not absorb them (Concin 2008, Noti 2003)

Alternatives

We do not have alternatives for Fenticonazole Nitrate since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Fenticonazole Nitrate is also known as


Fenticonazole Nitrate in other languages or writings:

Tradenames

Main tradenames from several countries containing Fenticonazole Nitrate in its composition:

Pharmacokinetics

Variable Value Unit
Bioavailability Der: 0, Vag: 1 %
Molecular weight 518 daltons

References

  1. Effik. Fenticonazol crema. Ficha técnica. 2010 Full text (in our servers)
  2. Concin N, Hofstetter G, Plattner B, Tomovski C, Fiselier K, Gerritzen K, Fessler S, Windbichler G, Zeimet A, Ulmer H, Siegl H, Rieger K, Concin H, Grob K. Mineral oil paraffins in human body fat and milk. Food Chem Toxicol. 2008 Abstract
  3. Noti A, Grob K, Biedermann M, Deiss U, Brüschweiler BJ. Exposure of babies to C15-C45 mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003 Abstract
  4. Novelli A, Periti E, Massi GB, Masi R, Mazzei T, Periti P. Systemic absorption of 3H-fenticonazole after vaginal administration of 1 gram in patients. J Chemother. 1991 Abstract

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