Last update: June 10, 2018

Δοβεσυλικό ασβέστιο

Low Risk for breastfeeding


Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.

A drug to which the ability to reduce capillary permeability is attributed. Used to treat diabetic retinopathy and hemorrhoids.
Administered orally in two daily doses.

Since the last update we have not found published data on its excretion in breastmilk, although the manufacturer indicates negligible excretion in breastmilk (OMPharma 2018, AEMPS 2017).

As there is less published information than for other drugs from the same group, safer known alternatives may be preferable during the neonatal period and in case of prematurity.

Alternatives

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

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Other names

Δοβεσυλικό ασβέστιο is Calcium Dobesilate in Greek.

Is written in other languages:

Group

Δοβεσυλικό ασβέστιο belongs to this group or family:

Tradenames

Main tradenames from several countries containing Δοβεσυλικό ασβέστιο in its composition:

List of 12 tradenames

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 80 %
Molecular weight 418 daltons
Protein Binding 20 - 25 %
Tmax 4 - 6 hours
T1/2 1 - 3 hours
Theoretical Dose 0,06 mg/Kg/d
Relative Dose 0,24 %

References

  1. OM Pharma. Dobesilate. Drug Summary. 2018 Full text (in our servers)
  2. AEMPS. Dobesilato. Ficha técnica. 2017 Full text (in our servers)
  3. Martinez-Zapata MJ, Vernooij RW, Uriona Tuma SM, Stein AT, Moreno RM, Vargas E, Capellà D, Bonfill Cosp X. Phlebotonics for venous insufficiency. Cochrane Database Syst Rev. 2016 Abstract
  4. DGF. Dirección General de Farmacia. Servicio Canario de la Salud. Listado de fármacos considerados de Utilidad terapéutica Baja (UTB). 2011 Full text (in our servers)

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