Last update: Nov. 29, 2019

Dipyridamole

Increased level of risk

New scientific evidences have driven the Apilam staff to update the level of risk associated to this product.
Former level of risk, which was Very Low Risk, is now set to Low Risk.

Level of risk reviewed on Nov. 29, 2019

Low Risk for breastfeeding


Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.

Inhibitor of platelet aggregation indicated in the prevention of post-operative thromboembolic complications associated with prosthetic heart valve.

Since the last update we have not found any published data on its excretion in breast milk.

Its pharmacokinetic characteristics (moderately elevated molecular weight, high plasma protein binding and large volume of distribution), make it very unlikely its excretion into breast milk in significant amounts.

Until there is more published data on this drug in relation to breastfeeding, safer known alternatives may be preferable, especially during the neonatal period and in cases of prematurity.

Alternatives

We do not have alternatives for Dipyridamole.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Dipyridamole in other languages or writings:

Group

Dipyridamole belongs to this group or family:

Tradenames

Main tradenames from several countries containing Dipyridamole in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 37 - 66 %
Molecular weight 505 daltons
Protein Binding 97 %
VD 1 - 2,5 l/Kg
pKa 14,97 -
Tmax 1 - 2,5 hours
T1/2 1 - 12 hours

References

  1. AEMPS-B.I. Dipiridamol. Ficha técnica. 2015 Full text (in our servers)
  2. Novopharm. Dipyridamole. Drug Summary. 2006 Full text (in our servers)

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