Last update: Feb. 27, 2018
Minimal risk for breastfeeding and infant.
Second generation anti-histaminic drug with low sedative effect.
Desloratadine es the active metabolite of loratadine. Its characteristics might be extrapolated to those of loratadine (So 2010).
Loratadine is excreted in non-significant amount into breast milk (Hilbert 1988). No side effects were observed in breastfed infants of treated mothers (Merlob 2002).
Various medical societies and expert consensus consider the use of loratadine safe during breastfeeding (So 2010, National Asthma Ed. 2004, Solhaug 2004, Ghaeli 1993).
The British Society of Immunology and Allergy rates loratadine compatible with breastfeeding (Powell 2007).
American Academy of Pediatrics: loratadine is a medication usually compatible with breastfeeding (AAP 2001).
The pharmacokinetic data of loratadine (higher percentage of protein binding, pKa acid and shorter half-life) would favor a lower excretion in breast milk.
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
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