Last update: June 13, 2019
Not risky for breastfeeding or infant.
Macrolide with similar actions and uses to erythromycin.
Indicated in respiratory infections, infections by mycobacteria and in gastric and duodenal ulcer associated with Helicobacter pylori.
Oral administration in two daily doses.
It is excreted in very small amounts in breast milk (Sedlmayr 1993). 12% of infants whose mothers took it had mild side effects such as gastroenteritis or somnolence (Goldstein 2009).
It is an antibiotic commonly used in Pediatrics.
Expert authors consider Azithromycin compatible with breastfeeding (Hale 2019, Briggs 2017, Butler 2014, Schaefer 2007, Goldstein 2009, Mahadevan 2006, Bar-Oz 2003, Chin 2001).
Some authors have linked direct and early exposure (first 15 days of life) to macrolides (especially Erythromycin) with hypertrophic pyloric stenosis (Almaramhy 2019, Lund 2014) and also through breast milk (Maheshwai 2007, Sorensen 2003, Stang 1986) but not others (Almaramhy 2019, Abdellatif 2019, Goldstein 2009) or not for macrolides other than erythromycin (Maheshwai 2007).
Be aware of false negative results of bacterial cultures obtained from febrile infants whose mothers are on antibiotics, as well as the possibility of gastroenteritis due to altered intestinal flora (Goldstein 2009, Ito 1993).
We do not have alternatives for Clarithromycin since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
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