Last update: July 31, 2016

Cefadroxil

Very Low Risk for breastfeeding


Safe. Compatible.
Not risky for breastfeeding or infant.

It is a First generation Cephalosporin.

Like other Cephalosporins, Cefadroxil is excreted into the breast milk in clinically non-significant amounts.

Be aware of the possibility of negative results of cultures done to febrile infants whose mothers are on antibiotics.

The American Academy of Pediatrics rates it as usually compatible with breastfeeding.

Alternatives

We do not have alternatives for Cefadroxil since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Cefadroxil is also known as


Cefadroxil in other languages or writings:

Group

Cefadroxil belongs to this group or family:

Tradenames

Main tradenames from several countries containing Cefadroxil in its composition:

Pharmacokinetics

Variable Value Unit
Bioavailability 100 %
Molecular weight 381 daltons
Protein Binding 20 %
VD 0,2 l/Kg
Tmax 1 - 2 hours
T1/2 1,5 hours
M/P ratio 0,01 - 0,02 -
Theoretical Dose 0,09 - 0,36 mg/Kg/d
Relative Dose 0,3 - 2,2 %
Relat.Ped.Dose 0,3 - 1,2 %

References

  1. Bar-Oz B, Bulkowstein M, Benyamini L, Greenberg R, Soriano I, Zimmerman D, Bortnik O, Berkovitch M. Use of antibiotic and analgesic drugs during lactation. Drug Saf. 2003 Abstract
  2. AAP - American Academy of Pediatrics Committee on Drugs. Transfer of drugs and other chemicals into human milk. Pediatrics. 2001 Sep;108(3):776-89. Abstract Full text (link to original source) Full text (in our servers)
  3. Fulton B, Moore LL. Antiinfectives in breastmilk. Part I: Penicillins and cephalosporins. J Hum Lact. 1992 Abstract
  4. Matsuda S. Transfer of antibiotics into maternal milk. Biol Res Pregnancy Perinatol. 1984;5(2):57-60. Abstract
  5. Kafetzis DA, Siafas CA, Georgakopoulos PA, Papadatos CJ. Passage of cephalosporins and amoxicillin into the breast milk. Acta Paediatr Scand. 1981 Abstract
  6. Takase Z, Shirafuji H, Uchida M. Clinical and laboratory studies of cefaclor in the field of obstetrics and gynecology. Chemotherapy (Tokyo). 1979;27(Suppl 7):666-72. 1979

Total visits

58,384

Help us improve this entry

How to cite this entry

Do you need more information or did not found what you were looking for?

   Write to us at elactancia.org@gmail.com

e-lactancia is a resource recommended by Academy of Breastfeeding Medicine from United States of America

Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM