Last update: May 25, 2018
Minimal risk for breastfeeding and infant.
Estrogen derived from estradiol with trophic effects on vaginal mucosa. Indicated in vulvo-vaginal atrophy
Topical use once or twice daily.
Up to the last update date we did not find published data on your excretion in breastmilk.
The low plasma absorption through the vaginal mucosa (Santos 2010), less than 1% (AEMPS 2018), makes the passage of a significant amount to breast milk unlikely.
Negative absorption has been demonstrated through the infant foreskin (Salmon 2013) and the absence of hormonal systemic effects in women (Santos 2010, Wolff 1982) with the topical use of promestriene.
Non-hormonal lubricants (cream, jelly or ovules) are preferred agents for treatment of vaginal dryness due to hypo-estrogenic stimulation than those estrogenic-containing topical agents.
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.
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