Last update: May 14, 2015

Aluminium Hydroxide

Very Low Risk for breastfeeding


Safe. Compatible.
Not risky for breastfeeding or infant.

Aluminum does not concentrate into breast milk.

After ingestion of antacids the Aluminum plasma levels increase from a basal-point of 7 μg/L to 55 μg/L at half-an-hour with a return to previous level 3 hours later.

Although a minimal amount of Aluminum may be found in the milk, there are not shown side-effects in the infant. Mother's milk has a mean concentration of 49 μg/L of Aluminum which is much lower than the amount of 180-700 μg/L found in artificial formulas.

Because of a low oral bioavailability the pass from the breast milk toward the infant's plasma is hampered, except in premature and newborn infants who may exhibit a higher intestinal absorption due to an increased permeability.

Avoid chronic or excessive use.

WHO Model List of Essential Medicines 2002: compatible with breastfeeding.

Alternatives

We do not have alternatives for Aluminium Hydroxide since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Aluminium Hydroxide is also known as Algeldrate.


Group

Aluminium Hydroxide belongs to this group or family:

Tradenames

Main tradenames from several countries containing Aluminium Hydroxide in its composition:

  • Acyline™. Contains other elements than Aluminium Hydroxide in its composition
  • Alu-Tab
  • Alucol
  • Aludrox
  • Alugel
  • Gelodrox™. Contains other elements than Aluminium Hydroxide in its composition
  • Kolantyl™. Contains other elements than Aluminium Hydroxide in its composition
  • Kompensan
  • Merankol Pastiglie™. Contains other elements than Aluminium Hydroxide in its composition
  • Polysilane Delalande™. Contains other elements than Aluminium Hydroxide in its composition

Pharmacokinetics

Variable Value Unit
Oral Bioavail. Baja - Low %
Molecular weight 78 daltons

References

  1. AEMPS. Algeldrato. Ficha técnica. 2014 Full text (in our servers)
  2. Burrell SA, Exley C. There is (still) too much aluminium in infant formulas. BMC Pediatr. 2010 Abstract Full text (link to original source) Full text (in our servers)
  3. Mahadevan U, Kane S. American gastroenterological association institute technical review on the use of gastrointestinal medications in pregnancy. Gastroenterology. 2006 Jul;131(1):283-311. Review. Abstract Full text (link to original source) Full text (in our servers)
  4. Richter JE. Review article: the management of heartburn in pregnancy. Aliment Pharmacol Ther. 2005 Nov 1;22(9):749-57. Review. Abstract Full text (in our servers)
  5. Dórea JG. Magnesium in human milk. J Am Coll Nutr. 2000 Apr;19(2):210-9. Review. Abstract
  6. Hagemann TM. Gastrointestinal medications and breastfeeding. J Hum Lact. 1998 Sep;14(3):259-62. Review. Abstract
  7. Broussard CN, Richter JE. Treating gastro-oesophageal reflux disease during pregnancy and lactation: what are the safest therapy options? Drug Saf. 1998 Oct;19(4):325-37. Review. Abstract
  8. Nagy E, Jobst K. The kinetics of aluminium-containing antacid absorption in man. Eur J Clin Chem Clin Biochem. 1994 Abstract
  9. Simmer K, Fudge A, Teubner J, James SL. Aluminum concentrations in infant formulae. J Paediatr Child Health. 1990 Abstract
  10. Feeley RM, Eitenmiller RR, Jones JB Jr, Barnhart H. Calcium, phosphorus, and magnesium contents of human milk during early lactation. J Pediatr Gastroenterol Nutr. 1983 May;2(2):262-7. Abstract

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