Last update July 5, 2014

Paraminosalicylic Acid

Very Low Risk

Safe. Compatible. Minimal risk for breastfeeding and infant.

Drug related to same group of 5-aminosalicylic Acid

It is excreted in tiny amounts into breast milk with no reported cases of harm effects except a case of mild gastroenteritis.


We do not have alternatives for Paraminosalicylic Acid since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Paraminosalicylic Acid is also known as


Paraminosalicylic Acid belongs to this group or family:


Main tradenames from several countries containing Paraminosalicylic Acid in its composition:


Variable Value Unit
Oral Bioavail. > 90 %
Molecular weight 153 daltons
Protein Binding 50 - 70 %
Tmax 1 - 4 hours
1 hours
M/P ratio 0.1 - 0.2 -
Theoretical Dose 0.15 mg/Kg/d
Relative Dose 0.1 %
Ped.Relat.Dose 0.01 - 0.1 %


  1. Arbex MA, Varella Mde C, Siqueira HR, Mello FA. Antituberculosis drugs: drug interactions, adverse effects, and use in special situations. Part 2: second line drugs. J Bras Pneumol. 2010 Abstract Full text (link to original source) Full text (in our servers)
  2. Silverman DA, Ford J, Shaw I, Probert CS. Is mesalazine really safe for use in breastfeeding mothers? Gut. 2005 Abstract Full text (link to original source) Full text (in our servers)
  3. Drobac PC, del Castillo H, Sweetland A, Anca G, Joseph JK, Furin J, Shin S. Treatment of multidrug-resistant tuberculosis during pregnancy: long-term follow-up of 6 children with intrauterine exposure to second-line agents. Clin Infect Dis. 2005 Jun 1;40(11):1689-92. Epub 2005 Apr 18. Abstract Full text (link to original source) Full text (in our servers)
  4. Jenss H, Weber P, Hartmann F. 5-Aminosalicylic acid and its metabolite in breast milk during lactation. Am J Gastroenterol. 1990 Abstract
  5. Nelis GF. Diarrhoea due to 5-aminosalicylic acid in breast milk. Lancet. 1989 Abstract
  6. Holdiness MR. Antituberculosis drugs and breast-feeding. Arch Intern Med. 1984 Abstract Full text (link to original source)

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e-lactancia is a resource recommended by AELAMA of Spain

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