Last update March 28, 2014

Fludeoxyglucose F18

High Risk

Poorly safe. Evaluate carefully. Use safer alternative or interrupt breastfeeding 3 to 7 T ½ (elimination half-lives). Read the Comment.

Radioisotope for PET scanning.

Pump-out breast milk and store it in refrigerator for some days before testing. After test is done, keep-on pumping milk and dispose it for the next 12-24 hours. Use stored milk to feed the baby. Choose the shortest half-life span radionucleotid as possible.

Alternatives

We do not have alternatives for Fludeoxyglucose F18.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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Other names

Fludeoxyglucose F18 is also known as


Group

Fludeoxyglucose F18 belongs to this group or family:

Tradenames

Main tradenames from several countries containing Fludeoxyglucose F18 in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 100 %
Tmax 0.5 hours
T½ 2 hours

References

  1. Leide-Svegborn S, Ahlgren L, Johansson L, Mattsson S. Excretion of radionuclides in human breast milk after nuclear medicine examinations. Biokinetic and dosimetric data and recommendations on breastfeeding interruption. Eur J Nucl Med Mol Imaging. 2016 Abstract
  2. Ko KH, Jung HK, Jeon TJ. Diffuse intense 18F-FDG uptake at PET in unilateral breast related to breastfeeding practice. Korean J Radiol. 2013 Abstract Full text (in our servers)
  3. Jamar F, Buscombe J, Chiti A, Christian PE, Delbeke D, Donohoe KJ, Israel O, Martin-Comin J, Signore A. EANM/SNMMI guideline for 18F-FDG use in inflammation and infection. J Nucl Med. 2013 Abstract Full text (in our servers)
  4. Abhyankar A, Joshi J, Basu S. FDG uptake in unilateral breast related to breastfeeding practice in a patient of pulmonary hydatid cyst. Clin Nucl Med. 2012 Abstract
  5. Segall G, Delbeke D, Stabin MG, Even-Sapir E, Fair J, Sajdak R, Smith GT; SNM. SNM practice guideline for sodium 18F-fluoride PET/CT bone scans 1.0. J Nucl Med. 2010 Abstract Full text (in our servers)
  6. Leide-Svegborn S. Radiation exposure of patients and personnel from a PET/CT procedure with 18F-FDG. Radiat Prot Dosimetry. 2010 Abstract
  7. Hendler D, Stemmer SM. Uncommon reason for high fluorodeoxyglucose positron emission tomography uptake. J Clin Oncol. 2010 Abstract Full text (in our servers)
  8. ICRP. Radiation dose to patients from radiopharmaceuticals. Addendum 3 to ICRP Publication 53. ICRP Publication 106. Annex D. Recommendations on breast-feeding interruptions, p. 163-165. Ann ICRP. 2008 Abstract Full text (link to original source) Full text (in our servers)
  9. Hicks RJ, Binns D, Stabin MG. Pattern of uptake and excretion of (18)F-FDG in the lactating breast. J Nucl Med. 2001 Abstract Full text (in our servers)

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