Last update Dec. 19, 2013


Low Risk

Possibly safe. Probably compatible. Mild risk possible. Follow up recommended. Read the Comment.

Cases of severe intestinal side effects have been reported.

On latest update no published data about breastfeeding were found. Because a rapid metabolic rate and poor oral absorption - when taken along with food - this drug is probably safe while breastfeeding. Safety would increase if a 3-hour period is observed before resuming breastfeeding.


We do not have alternatives for Alosetron.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.


Alosetron belongs to this group or family:


Main tradenames from several countries containing Alosetron in its composition:


Variable Value Unit
Oral Bioavail. 60 %
Molecular weight 294 daltons
Protein Binding 82 %
Tmax 1 hours
1.5 hours


  1. Alosetron Data Sheet 2010 Full text (in our servers)
  2. Mahadevan U, Kane S. American gastroenterological association institute technical review on the use of gastrointestinal medications in pregnancy. Gastroenterology. 2006 Jul;131(1):283-311. Review. Abstract Full text (link to original source) Full text (in our servers)
  3. Andresen V, Hollerbach S. Reassessing the benefits and risks of alosetron: what is its place in the treatment of irritable bowel syndrome? Drug Saf. 2004 Abstract

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