Last update: March 19, 2007

Troglitazone

High Risk for breastfeeding


Poorly safe. Evaluate carefully.
Use safer alternative or interrupt breastfeeding 3 to 7 T½.
Read the Comment.

It has been withdrawn from most countries because of severe liver toxic effects.
Tiazolidindion drugs increase the response to insulin.
Oral anti-diabetic drugs are useless for treatment of diabetes type 1. For diabetes type 2, diet and exercise are advisable. Breastfeeding helps to lower glucemia level. See section on Maternal diabetes mellitus

Alternatives

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Group

Troglitazone belongs to this group or family:

Tradenames

Main tradenames from several countries containing Troglitazone in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 53 %
Molecular weight 442 daltons
Protein Binding 99 %
Tmax 3 hours
T1/2 39 hours

References

We are working to add the scientific references of this product. It will be available soon. If you wish to have access to this information, please let us know by leaving your comment in the opinion section below.

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