Last update: Dec. 8, 2017
Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.
A 5-phosphodiesterase inhibitor with uses similar to sildenafil, used in the treatment of pulmonary hypertension (including in children: Takatsuki 2012), erectile dysfunction in men, Raynaud's syndrome and in other treatments due to its vasodilatory effect on smooth muscle.
Since the last update, we have not found published data on its excretion in breast milk.
Its high percentage of protein binding makes it unlikely that it will be transferred to milk in significant amounts, as in fact has been seen in another drug from the same therapeutic group, sildenafil.
Until there is more published data on this drug in relation to breastfeeding, safer known alternatives may be preferable, especially during the neonatal period and in case of prematurity.
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine from United States of America
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