Last update: July 31, 2018
Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.
Alpha-1 adrenergic blocker indicated in benign prostatic hyperplasia (BPH) in adult males.
Oral administration once a day.
Since the last update we have not found published data on its excretion in breastmilk.
Its high percentage of protein binding (EMA 2018) makes transfer into milk in significant amounts unlikely.
Its low oral bioavailability, reduced further with the consumption of fatty foods, such as milk (EMA 2018), hinders its transfer to the infant’s plasma from the breastmilk ingested, except in premature babies and the immediate neonatal period when there may be greater intestinal permeability.
Possible side effects are not serious or frequent (EMA 2018).
We do not have alternatives for Silodosin.
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
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