Last update: Nov. 7, 2015

σαλικυλικό οξύ

Very Low Risk for breastfeeding


Safe. Compatible.
Not risky for breastfeeding or infant.

It is topically used as a keratolytic, antiseptic, antifungal, dermatological and stomatological agent.

At last update no published data on excretion into breast milk were found .

Systemic absorption (distribution into the body) depends on the concentration of the product used and the duration of application. Absorption may reach 10 to 25% of the total amount applied on the skin. It is recommended not to use during lactation in large areas of skin or for prolonged periods.

Available data on the elimination of Acetylsalicylic acid (Aspirin-ASA) in breast milk indicates it is clinically insignificant.
No cases have been reported on Reye's syndrome by ASA through the breast milk which is considered very unlikely to occur with isolated and/or small doses used as antithrombotic treatments and anti-abortion measures, even less after application on the skin or topically in the mouth.

Do not apply on the breast to prevent ingestion by the infant. If necessary, apply it after the feed and wipe it off thoroughly with water before the next feed.

Alternatives

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

σαλικυλικό οξύ is Salicylic Acid in Greek.

Is written in other languages:

Groups

σαλικυλικό οξύ belongs to these groups or families:

Tradenames

Main tradenames from several countries containing σαλικυλικό οξύ in its composition:

Pharmacokinetics

Variable Value Unit
Molecular weight 138 daltons
Tmax 1,4 - 3,5 (derm.) hours

References

  1. Murase J. Safe Skin Care During Pregnancy and Breastfeeding. Fact Sheet. For the media. American Academy of Dermatology. 2015 Full text (link to original source) Full text (in our servers)
  2. Madan RK, Levitt J. A review of toxicity from topical salicylic acid preparations. J Am Acad Dermatol. 2014 Abstract Full text (link to original source) Full text (in our servers)
  3. Kong YL, Tey HL. Treatment of acne vulgaris during pregnancy and lactation. Drugs. 2013 Abstract
  4. Fung W, Orak D, Re TA, Haughey DB. Relative bioavailability of salicylic acid following dermal application of a 30% salicylic acid skin peel preparation. J Pharm Sci. 2008 Abstract
  5. Unsworth J, d'Assis-Fonseca A, Beswick DT, Blake DR. Serum salicylate levels in a breast fed infant. Ann Rheum Dis. 1987 Abstract Full text (link to original source) Full text (in our servers)

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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine from United States of America

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