Last update: Dec. 8, 2017

Prednicarbate

Very Low Risk for breastfeeding


Safe. Compatible.
Not risky for breastfeeding or infant.

High potency topical steroid.

Since the last update we have not found published data on its excretion in breast milk.

Because of a low absorption through skin, 0.1 - 3% (Dermik 2010, Novag 1998), significant excretion into breast milk is unlikely.

Whenever a treatment for nipple eczema or dermatitis is required the lowest potency steroid compound should be used (hydrocortisone). It should be applied right after the feed to make sure it has disappeared before the next nursing occurs. Otherwise, wipe cream out with a clean gauze.

Do not continuously use for longer than a week. Reportedly, a case of mineral-steroid toxicity has occurred due to continuous use of cream on the nipple (De Stefano 1983).

It is advisable to avoid the application to the nipple of creams, gels and other topical products containing paraffin (mineral oil) so that the infant does not absorb them (Concin 2008, Noti 2003).

Alternatives

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Prednicarbate in other languages or writings:

Group

Prednicarbate belongs to this group or family:

Tradenames

Main tradenames from several countries containing Prednicarbate in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. Dermat. 0,1 %
Molecular weight 488 daltons

References

  1. Dermik. Prednicarbate. Drug Summary. 2010 Full text (in our servers)
  2. Concin N, Hofstetter G, Plattner B, Tomovski C, Fiselier K, Gerritzen K, Fessler S, Windbichler G, Zeimet A, Ulmer H, Siegl H, Rieger K, Concin H, Grob K. Mineral oil paraffins in human body fat and milk. Food Chem Toxicol. 2008 Abstract
  3. Noti A, Grob K, Biedermann M, Deiss U, Brüschweiler BJ. Exposure of babies to C15-C45 mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003 Abstract
  4. Novag. Prednicarbato. Ficha técnica. 1998 Full text (in our servers)
  5. De Stefano P, Bongo IG, Borgna-Pignatti C, Severi F. Factitious hypertension with mineralocorticoid excess in an infant. Helv Paediatr Acta. 1983 Abstract

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