Last update: June 17, 2017

Huperzia serrata

Very High Risk for breastfeeding


Very unsafe. Contraindicated.
Use of an alternative or cessation of breastfeeding.

A plant native to China. There is also a patented medicine called Jin Bu Huan which contains this plant (Horowitz 1996).

It is used in traditional Chinese medicine which attributes to it analgesic, sedative and other properties, none of which have been clearly scientifically proven (Fu 2011). There is little published literature.

Since the last update we have not published data on its excretion in breast milk.

It has caused cases of acute hepatitis and extreme fatigue in adults (Teschke 2012-2014, Conti 2008, Divinsky 2002, McRae 2002, Stickel 2000, Picciotto 1998, Horowitz 1996, Kaptchuk 1995, CDC 1994, Woolf 1994, CDC 1993), drowsiness, muscle weakness, respiratory depression and bradycardia in children (Horowitz 1996, CDC 1993) and has been withdrawn from sale in several countries (Health Canada 2008).

Precautions when taking plant preparations:
1. Ensure that they are from a reliable source: poisoning has occurred due to confusing one plant with another with toxic properties, as well as poisoning from heavy metals extracted from the ground and food poisoning due to contamination with bacteria or fungi.
2. Do not take in large amounts; follow recommendations from professional experts in phytotherapy. "Natural" products are not always good in any quantity: plants contain active substances from which much of our traditional pharmacopoeia has been obtained and can result in poisoning or act as endocrine disruptors if taken in excessive amounts or time periods.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Huperzia serrata is Jin Bu Huan in Latin, botanical name.

Is written in other languages:

Huperzia serrata is also known as

Group

Huperzia serrata belongs to this group or family:

Tradenames

Main tradenames from several countries containing Huperzia serrata in its composition:

References

  1. Teschke R, Zhang L, Long H, Schwarzenboeck A, Schmidt-Taenzer W, Genthner A, Wolff A, Frenzel C, Schulze J, Eickhoff A. Traditional Chinese Medicine and herbal hepatotoxicity: a tabular compilation of reported cases. Ann Hepatol. 2015 Abstract
  2. Teschke R. Traditional Chinese Medicine Induced Liver Injury. J Clin Transl Hepatol. 2014 Abstract
  3. Teschke R, Wolff A, Frenzel C, Schulze J, Eickhoff A. Herbal hepatotoxicity: a tabular compilation of reported cases. Liver Int. 2012 Abstract
  4. Fu LM, Li JT. A systematic review of single chinese herbs for Alzheimer's disease treatment. Evid Based Complement Alternat Med. 2011 Abstract
  5. Conti E, De Checchi G, Mencarelli R, Pinato S, Rovere P. Lycopodium similiaplex-induced acute hepatitis: a case report. Eur J Gastroenterol Hepatol. 2008 Abstract
  6. Health/Santé Canada Warning: Health Canada Warns Consumers Not to Use Jin Bu Huan Anodyne Tablets Due to Potential Health Risk. News Room 2008 Full text (link to original source) Full text (in our servers)
  7. McRae CA, Agarwal K, Mutimer D, Bassendine MF. Hepatitis associated with Chinese herbs. Eur J Gastroenterol Hepatol. 2002 Abstract
  8. Divinsky M. Case report: jin bu huan--not so benign herbal medicine. Can Fam Physician. 2002 Abstract
  9. Stickel F, Egerer G, Seitz HK. Hepatotoxicity of botanicals. Public Health Nutr. 2000 Abstract
  10. Picciotto A, Campo N, Brizzolara R, Giusto R, Guido G, Sinelli N, Lapertosa G, Celle G. Chronic hepatitis induced by Jin Bu Huan. J Hepatol. 1998 Abstract
  11. Horowitz RS, Feldhaus K, Dart RC, Stermitz FR, Beck JJ. The clinical spectrum of Jin Bu Huan toxicity. Arch Intern Med. 1996 Abstract
  12. Kaptchuk TJ. Acute hepatitis associated with jin bu huan. Ann Intern Med. 1995 Abstract
  13. [No authors listed] From the Centers for Disease Control and Prevention. Jin bu huan toxicity in adults--Los Angeles, 1993. JAMA. 1994 Abstract
  14. Woolf GM, Petrovic LM, Rojter SE, Wainwright S, Villamil FG, Katkov WN, Michieletti P, Wanless IR, Stermitz FR, Beck JJ, Vierling JM. Acute hepatitis associated with the Chinese herbal product jin bu huan. Ann Intern Med. 1994 Abstract
  15. Centers for Disease Control and Prevention (CDC).. Jin bu huan toxicity in children--Colorado, 1993. MMWR Morb Mortal Wkly Rep. 1993 Abstract
  16. Centers for Disease Control and Prevention (CDC).. Jin bu huan toxicity in adults--Los Angeles, 1993. MMWR Morb Mortal Wkly Rep. 1993 Abstract

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