Last update: July 16, 2015

Formoterol

Very Low Risk for breastfeeding


Safe. Compatible.
Minimal risk for breastfeeding and infant.

Bronchodilator of long-lasting action.

At latest update no published data on excretion into breast milk were found.

Terbutaline which is a compound closely related to Formoterol is excreted into breast milk in non-significant amount.
Salmeterol, another compound with similar characteristics, is also non-significantly excreted.
With a relatively high molecular weight, excretion into breast milk seems unlikely.

Expert consensus states that the use of inhaled bronchodilators is compatible with breastfeeding due to a minimal absorption and low levels achieved in the mother's plasma.

Inhaled therapy with bronchodilators is preferred since they use a lower dose (less likelihood of excretion into milk)

Alternatives

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Formoterol is also known as


Formoterol in other languages or writings:

Group

Formoterol belongs to this group or family:

Tradenames

Main tradenames from several countries containing Formoterol in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. > 90% %
Molecular weight 805 daltons
Protein Binding 64 %
Tmax 0,1 hours
T1/2 10 hours

References

  1. National Asthma Education and Prevention Program Asthma and Pregnancy Working Group. Managing asthma during pregnancy: recommendations for pharmacologic treatment-2004 update. 2004;1-57. 2004 Full text (link to original source) Full text (in our servers)
  2. National Asthma Education and Prevention Program Asthma and Pregnancy Working Group. Quick Reference from the Working Group Report on Managing asthma during pregnancy: recommendations for pharmacologic treatment-2004 update. 2004;1-12. 2004 Full text (link to original source) Full text (in our servers)
  3. Cazzola M, Testi R, Matera MG. Clinical pharmacokinetics of salmeterol. Clin Pharmacokinet. 2002 Abstract
  4. Nelson-Piercy C. Asthma in pregnancy. Thorax. 2001 Abstract Full text (link to original source) Full text (in our servers)
  5. McDonald CF, Burdon JG. Asthma in pregnancy and lactation. A position paper for the Thoracic Society of Australia and New Zealand. Med J Aust. 1996 Abstract
  6. Ellsworth A. Pharmacotherapy of asthma while breastfeeding. J Hum Lact. 1994 Abstract
  7. Lindberg C, Boréus LO, de Château P, Lindström B, Lönnerholm G, Nyberg L. Transfer of terbutaline into breast milk. Eur J Respir Dis Suppl. 1984 Abstract
  8. Lönnerholm G, Lindström B. Terbutaline excretion into breast milk. Br J Clin Pharmacol. 1982 Abstract Full text (link to original source) Full text (in our servers)
  9. Boréus LO, de Château PU. Terbutaline in breast milk. Br J Clin Pharmacol. 1982 Abstract Full text (link to original source) Full text (in our servers)

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