Last update: Jan. 24, 2017
Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.
Anticholinergic and smooth-muscle relaxant with antimuscarinic action which is used to relieve spasticity, inflammation, pain and incontinence of the urine bladder tract.
At latest update relevant published data on its excretion into breast milk were not found.
The antimuscarinic effect may reduce milk production (De Martino 1980, Bizarro 1980), albeit only during the first weeks postpartum.
Side effects occur very rarely with a rather low risk during lactation when timely used. Monitoring of milk production and anticholinergic symptoms in the infant such as irritability, nausea or constipation would be desirable.
Until more published data on this drug related to breastfeeding is available, an alternative with a known pharmacokinetic profile that should appear safer while breastfeeding (higher protein-binding capacity, lower half-life span and lower oral bioavailability) may be preferable, especially during the neonatal period and in case of prematurity.
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.
e-lactancia is a resource recommended by Academy of Breastfeeding Medicine from United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM