Last update: Nov. 17, 2014

Electronic nicotine delivery system (ENDS)

Low Risk for breastfeeding


Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.

Nicotine levels in the blood of the mother (hence in mother's milk as well) are ten times lower than that reached in women's who smoke normal cigarettes. However, because of concomitant appearance of chemical products in the electronic cigarettes that are considered to be toxic, the lack of information of effects on the heath welfare and a high risk of becoming a long-lasting substitute of tobacco consumption, it should not be used as a replacement therapy. For this purpose is recommended the use of nicotine patches or chewing gum.

Nicotine excretion is lower at two hours after inhalation.

Alternatives

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.
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Other names

Electronic nicotine delivery system (ENDS) is also known as Electronic cigarette. Here it is a list of alternative known names::


Groups

Electronic nicotine delivery system (ENDS) belongs to these groups or families:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 30 %
Molecular weight 162 daltons
Protein Binding 5 %
Tmax 2 - 4 hours
T1/2 2 hours
M/P ratio 1,5 - 3 -

References

  1. Baraona LK, Lovelace D, Daniels JL, McDaniel L. Tobacco Harms, Nicotine Pharmacology, and Pharmacologic Tobacco Cessation Interventions for Women. J Midwifery Womens Health. 2017 Abstract
  2. Reece-Stremtan S, Marinelli KA. ABM Clinical Protocol #21: Guidelines for Breastfeeding and Substance Use or Substance Use Disorder, Revised 2015. Breastfeed Med. 2015 Abstract Full text (link to original source) Full text (in our servers)
  3. ABM Protocolo clínico de la ABM n.º 21: Pautas para la lactancia y el consumo de sustancias o trastorno por consumo de sustancias, revisado en 2015. Breastfeed Med. 2015 Full text (link to original source) Full text (in our servers)
  4. Goniewicz ML, Knysak J, Gawron M, Kosmider L, Sobczak A, Kurek J, Prokopowicz A, Jablonska-Czapla M, Rosik-Dulewska C, Havel C, Jacob P 3rd, Benowitz N. Levels of selected carcinogens and toxicants in vapour from electronic cigarettes. Tob Control. 2014 Abstract
  5. Benowitz NL. Emerging nicotine delivery products. Implications for public health. Ann Am Thorac Soc. 2014 Abstract
  6. Drummond MB, Upson D. Electronic cigarettes. Potential harms and benefits. Ann Am Thorac Soc. 2014 Abstract
  7. Harrell PT, Simmons VN, Correa JB, Padhya TA, Brandon TH. Electronic nicotine delivery systems (\e-cigarettes\): review of safety and smoking cessation efficacy. Otolaryngol Head Neck Surg. 2014 Abstract
  8. Besaratinia A, Tommasi S. Electronic cigarettes: the road ahead. Prev Med. 2014 Abstract
  9. Hecht SS, Carmella SG, Kotandeniya D, Pillsbury ME, Chen M, Ransom BW, Isaksson Vogel R, Thompson E, Murphy SE, Hatsukami DK. Evaluation of Toxicant and Carcinogen Metabolites in the Urine of e-Cigarette Users Versus Cigarette Smokers. Nicotine Tob Res. 2014 Abstract
  10. Sachs HC; Committee On Drugs. The transfer of drugs and therapeutics into human breast milk: an update on selected topics. Pediatrics. 2013 Sep;132(3):e796-809. Abstract Full text (link to original source) Full text (in our servers)
  11. Rowe H, Baker T, Hale TW. Maternal medication, drug use, and breastfeeding. Pediatr Clin North Am. 2013 Feb;60(1):275-94. Abstract
  12. Carson KV, Brinn MP, Robertson TA, To-A-Nan R, Esterman AJ, Peters M, Smith BJ. Current and emerging pharmacotherapeutic options for smoking cessation. Subst Abuse. 2013 Abstract Full text (link to original source) Full text (in our servers)
  13. Einarson A, Riordan S. Smoking in pregnancy and lactation: a review of risks and cessation strategies. Eur J Clin Pharmacol. 2009 Abstract
  14. Dahlström A, Ebersjö C, Lundell B. Nicotine in breast milk influences heart rate variability in the infant. Acta Paediatr. 2008 Abstract

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