Last update: March 8, 2007

Dorzolamide-Hcl

Low Risk for breastfeeding


Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.

It inhibits activity of carbonic anhydrase.Systemic absorption is minimal. There have not been problems except when a maternal overdose was absorbed. Like most ophthalmologic compounds for topical use a low dose and poor absorption make it compatible with breastfeeding. No untoward effect has been described.

Alternatives

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Group

Dorzolamide-Hcl belongs to this group or family:

Tradenames

Main tradenames from several countries containing Dorzolamide-Hcl in its composition:

Pharmacokinetics

Variable Value Unit
Molecular weight 324 daltons
Protein Binding 33 %
T1/2 2880 hours

References

  1. Johnson SM, Martinez M, Freedman S. Management of glaucoma in pregnancy and lactation. Surv Ophthalmol. 2001 Mar-Apr;45(5):449-54. Abstract

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