Last update: Aug. 21, 2016

Cidofovir (Topical Use)

Low Risk for breastfeeding


Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.

Used for treatment of CMV retinitis in HIV patients.

Toxic effect on kidney function

Topically used for intralesional treatment of recurrent laringeal papillomatosis caused by the Human Papilloma Virus, even in infants and children, without side effects. Serum level after intralesional injection varies from 0 to 0.4 mg/L, which is fifty times lower than after intravenous administration.

Excretion into breast milk is unknown but absorption by the intestine should be very poor.

Alternatives

We do not have alternatives for Cidofovir (Topical Use).

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Cidofovir (Topical Use) is also known as


Group

Cidofovir (Topical Use) belongs to this group or family:

Pharmacokinetics

Variable Value Unit
Bioavailability <10 %
Molecular weight 279 daltons
Protein Binding 10 %
T1/2 17 hours

References

  1. Concin N, Hofstetter G, Plattner B, Tomovski C, Fiselier K, Gerritzen K, Fessler S, Windbichler G, Zeimet A, Ulmer H, Siegl H, Rieger K, Concin H, Grob K. Mineral oil paraffins in human body fat and milk. Food Chem Toxicol. 2008 Abstract
  2. Noti A, Grob K, Biedermann M, Deiss U, Brüschweiler BJ. Exposure of babies to C15-C45 mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003 Abstract

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