Last update: Oct. 15, 2016

Cefdinir

Very Low Risk for breastfeeding


Safe. Compatible.
Not risky for breastfeeding or infant.

Third-generation cephalosporin for oral administration.

At latest update no published data on excretion into breast milk were found. According to the manufacturer it is not excreted into breast milk (Abbott 2007).

Most cephalosporins are excreted into milk in insignificant amounts from a therapeutic point of view without reported complications in infants.
Cephalosporins are widely used in the Pediatric practice with a good tolerance, even in the neonatal period, so it is very unlikely that in small amounts through milk would be a cause of problems in the infant.

Red discoloration of stools would appear when combined with iron supplements (Lancaster 2008).

Be aware of the possibility of false negative results of cultures in febrile infants whose mothers are taking antibiotics as well as the possibility of gastroenteritis (Ito 1993) by altering the intestinal flora.

Alternatives

We do not have alternatives for Cefdinir since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Cefdinir in other languages or writings:

Group

Cefdinir belongs to this group or family:

Tradenames

Main tradenames from several countries containing Cefdinir in its composition:

Pharmacokinetics

Variable Value Unit
Bioavailability 16 - 25 %
Molecular weight 395 daltons
Protein Binding 60 - 70 %
VD 0,35 l/Kg
Tmax 2 - 4 hours
T1/2 1.7 ± 0.6 hours

References

  1. Rowe H, Baker T, Hale TW. Maternal medication, drug use, and breastfeeding. Pediatr Clin North Am. 2013 Feb;60(1):275-94. Abstract
  2. Lancaster J, Sylvia LM, Schainker E. Nonbloody, red stools from coadministration of cefdinir and iron-supplemented infant formulas. Pharmacotherapy. 2008 Abstract
  3. Abbott. Omnicef. Drug Summary. 2007 Full text (in our servers)
  4. Bar-Oz B, Bulkowstein M, Benyamini L, Greenberg R, Soriano I, Zimmerman D, Bortnik O, Berkovitch M. Use of antibiotic and analgesic drugs during lactation. Drug Saf. 2003 Abstract
  5. Fulton B, Moore LL. Antiinfectives in breastmilk. Part I: Penicillins and cephalosporins. J Hum Lact. 1992 Abstract

Total visits

4,189

Help us improve this entry

How to cite this entry

Do you need more information or did not found what you were looking for?

   Write to us at elactancia.org@gmail.com

e-lactancia is a resource recommended by Confederación Nacional de Pediatría (CONAPEME) from Mexico

Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM