Last update: July 12, 2017

Bismuth Citrate

Very Low Risk for breastfeeding


Safe. Compatible.
Not risky for breastfeeding or infant.

Bismuth salts are used alone or together with other components in preparations against gastritis and diarrhea.
Bismuth salicylate contains about 60% bismuth and 40% salicylate.

At latest update no published data on excretion into breast milk were found.

Bismuth is not absorbed into the systemic circulation of the mother.

There may be a risk of absorption of salicylate in the case of bismuth salicylate, although in small quantity (<1% of the maternal dose), but no cases of Reye's syndrome have been reported after taking bismuth salicylate or other non-acetylated salicylate compounds.

Due to the otherwise minimum risk of Reye's syndrome and the indiscriminate use of bismuth subsalicylate for treatment of gastroenteritis cannot be justifiable since most of gastroenteritis do not require medication instead a simply adequate hydration, a safer alternative should be desirable while breastfeeding, like the other salts of bismuth (citrate, etc).

Alternatives

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Bismuth Citrate is also known as Bismuth salts . Here it is a list of alternative known names::


Bismuth Citrate in other languages or writings:

Tradenames

Main tradenames from several countries containing Bismuth Citrate in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. Baja - Poor %
Molecular weight 362 daltons

References

  1. Chen LH, Zeind C, Mackell S, LaPointe T, Mutsch M, Wilson ME. Breastfeeding travelers: precautions and recommendations. J Travel Med. 2010 Jan-Feb;17(1):32-47. Abstract Full text (link to original source) Full text (in our servers)
  2. Mahadevan U, Kane S. American gastroenterological association institute technical review on the use of gastrointestinal medications in pregnancy. Gastroenterology. 2006 Jul;131(1):283-311. Review. Abstract Full text (link to original source) Full text (in our servers)
  3. Nice FJ, Snyder JL, Kotansky BC. Breastfeeding and over-the-counter medications. J Hum Lact. 2000 Nov;16(4):319-31. Review. Erratum in: J Hum Lact 2001 Feb;17(1):90. Abstract
  4. Anderson PO. Drug use during breast-feeding. Clin Pharm. 1991 Abstract
  5. Findlay JW, DeAngelis RL, Kearney MF, Welch RM, Findlay JM. Analgesic drugs in breast milk and plasma. Clin Pharmacol Ther. 1981 Abstract

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