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Last update: July 10, 2014

Ava Pepper

Very High Risk for breastfeeding

Very unsafe. Contraindicated.
Use of an alternative or cessation of breastfeeding.

Rhizomes are used.
It contains kavapirone and resin.
Unproved effects: hypnotic, spasmolytic, sedative.
Indication after Commission E of German Ministry of Health: insomnia, anxiety.
Very dangerous if mixed with alcohol.
The Spanish Agency for Drugs has withdrawn all kava-kava containing products from the market after several cases of overwhelming hepatic failure have occurred.

Alternatives

We do not have alternatives for Ava Pepper.

Very Low risk.

Safe. Compatible. Minimal risk for breastfeeding and infant.

More information

Low Risk.

Moderately safe. Probably compatible. Mild risk possible. Follow up recommended. Read the Comment.

More information

High Risk.

Poorly safe. Evaluate carefully. Use safer alternative or interrupt breastfeeding 3 to 7 T ½ (elimination half-lives). Read the Comment.

More information

Very High Risk.

Very unsafe. Contraindicated. Use of an alternative or cessation of breastfeeding.

More information

Very Low risk.

Safe. Compatible. Minimal risk for breastfeeding and infant.

More information

Low Risk.

Moderately safe. Probably compatible. Mild risk possible. Follow up recommended. Read the Comment.

More information

High Risk.

Poorly safe. Evaluate carefully. Use safer alternative or interrupt breastfeeding 3 to 7 T ½ (elimination half-lives). Read the Comment.

More information

Very High Risk.

Very unsafe. Contraindicated. Use of an alternative or cessation of breastfeeding.

More information

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

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Other names

Ava Pepper is also known as Kava Kava. Here it is a list of alternative known names::

Piper Methysticum

Group

Ava Pepper belongs to this group or family:

NoATC FI1: Phytotherapy, Systemic Use

References

List of 6 references

Bunchorntavakul C, Reddy KR. Review article: herbal and dietary supplement hepatotoxicity. Aliment Pharmacol Ther. 2013 Abstract Full text (link to original source) Full text (in our servers)
Mannion C, Mansell D. Breastfeeding self-efficacy and the use of prescription medication: a pilot study. Obstet Gynecol Int. 2012;2012:562704. Abstract Full text (link to original source) Full text (in our servers)
Chitturi S, Farrell GC. Hepatotoxic slimming aids and other herbal hepatotoxins. J Gastroenterol Hepatol. 2008 Abstract Full text (in our servers)
Zhou S, Koh HL, Gao Y, Gong ZY, Lee EJ. Herbal bioactivation: the good, the bad and the ugly. Life Sci. 2004 Abstract
MSC - Ministerio de Sanidad y Consumo de España. ORDEN SCO/190/2004, de 28 de enero, por la que se establece la lista de plantas cuya venta al público queda prohibida o restringida por razón de su toxicidad. BOE 2004; 32:5061-6065 Full text (link to original source) Full text (in our servers)
WHO. World Health Organization. Geneva. WHO monographs on selected medicinal plants. Volume 2. WHO monographs. 1999 Full text (link to original source) Full text (in our servers)

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