Last update: Aug. 12, 2014

Atropine Ophtalmic Use

Very Low Risk for breastfeeding


Safe. Compatible.
Not risky for breastfeeding or infant.

Like most ophthalmologic compounds for topical use a low dose and poor absorption make it compatible with breastfeeding. Pomade is preferred. When applying press with a finger on conjunctival sac for 2 minutes to avoid systemic absorption.

American Academy of Pediatrics rates it as a safe drug.

Alternatives

We do not have alternatives for Atropine Ophtalmic Use since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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José María Paricio, founder of e-lactancia.
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Group

Atropine Ophtalmic Use belongs to this group or family:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 90 %
Molecular weight 289 daltons
Protein Binding 14 - 22 %
VD 2 - 4 l/Kg
Tmax 1 hours
T1/2 4,3 hours

References

  1. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Full text (link to original source) Full text (in our servers)
  2. AAP - American Academy of Pediatrics Committee on Drugs. Transfer of drugs and other chemicals into human milk. Pediatrics. 2001 Sep;108(3):776-89. Abstract Full text (link to original source) Full text (in our servers)
  3. Hagemann TM. Gastrointestinal medications and breastfeeding. J Hum Lact. 1998 Sep;14(3):259-62. Review. Abstract
  4. Bizzarro A, Iannucci F, Tolino A, Soricelli A, Guarino G, Verdoliva A. Inhibiting effect of atropine on prolactin blood levels after stimulation with TRH. Clin Exp Obstet Gynecol. 1980 Abstract
  5. De Martino F, De Matteo A, L'Abbate V, Soricelli A, Fontana A, Petrenga E, Cesarone M. [Inhibitory effects of atropine on serum prolactin levels after TRH stimulation]. Boll Soc Ital Biol Sper. 1980 Abstract

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