Last update: Dec. 21, 2013

Atomoxetine

High Risk for breastfeeding


Poorly safe. Evaluate carefully.
Use safer alternative or interrupt breastfeeding 3 to 7 T ½ (elimination half-lives).
Read the Comment.

Psycho-stimulant used for treatment of Attention Deficit and Hyperactivity Disorder.

On latest update relevant data on breastfeeding was not found.

Although a high plasma protein binding makes excretion into breast milk likely very low, until more information concerning breastfeeding is available, a safer alternative is preferred.

Alternatives

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

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Other names

Atomoxetine is also known as


Group

Atomoxetine belongs to this group or family:

Tradenames

Main tradenames from several countries containing Atomoxetine in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 63 - 94 %
Molecular weight 291 daltons
Protein Binding 98 %
VD 0,9 l/Kg
Tmax 1 - 2 hours
T1/2 5 - 21 hours

References

  1. Cui YM, Teng CH, Pan AX, Yuen E, Yeo KP, Zhou Y, Zhao X, Long AJ, Bangs ME, Wise SD. Atomoxetine pharmacokinetics in healthy Chinese subjects and effect of the CYP2D6*10 allele. Br J Clin Pharmacol. 2007 Abstract Full text (in our servers)
  2. Sauer JM, Ring BJ, Witcher JW. Clinical pharmacokinetics of atomoxetine. Clin Pharmacokinet. 2005 Abstract

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