Last update: Jan. 7, 2014

Articaine

Very Low Risk for breastfeeding


Compatible.
Not risky for breastfeeding or infant.

On latest update relevant data on breastfeeding was not found.

Similar chemical structure to Lidocaine which is excreted into breast milk in minimal amount.

Anesthetic drugs for topical use both dermatological and odontological have almost nil absorption when properly used.

Alternatives

We do not have alternatives for Articaine since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Articaine is also known as


Group

Articaine belongs to this group or family:

Tradenames

Main tradenames from several countries containing Articaine in its composition:

Pharmacokinetics

Variable Value Unit
Molecular weight 321 daltons
Protein Binding 50 - 90 %
Tmax 0,25 hours
T1/2 0,3 - 2,4 hours

References

  1. Nizharadze N, Mamaladze M, Chipashvili N, Vadachkoria D. Articaine - the best choice of local anesthetic in contemporary dentistry. Georgian Med News. 2011 Abstract
  2. Oertel R, Rahn R, Kirch W. Clinical pharmacokinetics of articaine. Clin Pharmacokinet. 1997 Abstract
  3. van Oss GE, Vree TB, Baars AM, Termond EF, Booij LH. Pharmacokinetics, metabolism, and renal excretion of articaine and its metabolite articainic acid in patients after epidural administration. Eur J Anaesthesiol. 1989 Abstract
  4. Van Oss GE, Vree TB, Baars AM, Termond EF, Booij LH. Clinical effects and pharmacokinetics of articainic acid in one volunteer after intravenous administration. Pharm Weekbl Sci. 1988 Abstract

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